2. Gene
  3. Dock7 - dedicator of cytokinesis 7 Gene

Dock7 - dedicator of cytokinesis 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gm430; 3110056M06Rik

基因 ID: 67299 | 基因类型: protein coding

关于 Dock7

功能概要

Enables small GTPase binding activity. Involved in interkinetic nuclear migration; negative regulation of cold-induced thermogenesis; and regulation of neurogenesis. Acts upstream of or within hematopoietic progenitor cell differentiation and pigmentation. Predicted to be located in cell projection. Predicted to be part of COP9 signalosome. Is expressed in several structures, including alimentary system; central nervous system; lung; placenta; and sensory organ. Used to study platelet storage pool deficiency. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 23. Orthologous to human DOCK7 (dedicator of cytokinesis 7). [provided by Alliance of Genome Resources, Apr 2022]

Dock7 基因产物(8)

mRNA Protein Name
NM_001290636.1 NP_001277565.1 dedicator of cytokinesis protein 7 isoform 1
NM_001369285.1 NP_001356214.1 dedicator of cytokinesis protein 7 isoform 3
NM_001369286.1 NP_001356215.1 dedicator of cytokinesis protein 7 isoform 4
NM_026082.5 NP_080358.3 dedicator of cytokinesis protein 7 isoform 2
NM_001290636.1 NP_001277565.1 dedicator of cytokinesis protein 7 isoform 1
NM_001369285.1 NP_001356214.1 dedicator of cytokinesis protein 7 isoform 3
NM_001369286.1 NP_001356215.1 dedicator of cytokinesis protein 7 isoform 4
NM_026082.5 NP_080358.3 dedicator of cytokinesis protein 7 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19129230 MGI
enables small GTPase binding IDA
IDA: 通过直接分析推断
16982419 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within hematopoietic progenitor cell differentiation IGI
IGI: 通过遗传相互作用推断
24029230 MGI
involved in interkinetic nuclear migration IMP
IMP: 通过突变表型推断
22842144 MGI
involved in negative regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
23553822 MGI
acts upstream of or within pigmentation IMP
IMP: 通过突变表型推断
2379821 MGI
involved in postsynaptic specialization assembly IDA
IDA: 通过直接分析推断
21041412 MGI
involved in postsynaptic specialization assembly IMP
IMP: 通过突变表型推断
21041412 MGI
involved in regulation of neurogenesis IMP
IMP: 通过突变表型推断
22842144 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in neuromuscular junction IDA
IDA: 通过直接分析推断
21041412 MGI
is active in neuromuscular junction IMP
IMP: 通过突变表型推断
21041412 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dedicator of cytokinesis protein 7

protein moonlight

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03929 DOCK7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21558 Dock7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28076 Dock7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dock7 NCBI NCBI:85440
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