SRPRA - SRP receptor subunit alpha Gene

中文名称：SRP 受体亚基α

种属: Homo sapiens

同用名: DP; SRPR; Sralpha

基因 ID: 6734 | 基因类型: protein coding

关于 SRPRA

Cytogenetic location: 11q24.2 Genomic coordinates (GRCh38): 11:126,235,930-126,268,895 (from NCBI)

This gene has 7 transcripts (splice variants), 211 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 41.3), salivary gland (RPKM 33.7) and 25 other tissues.

功能概要

该基因编码内质网信号识别颗粒受体的一个亚基，该亚基与信号识别颗粒一起参与信号序列标记的分泌蛋白和膜蛋白穿过内质网的靶向和转运。可变剪接导致多个转录本变体。[RefSeq 提供，2010 年 4 月]

The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

SRPRA 基因产物(2)

mRNA	Protein	Name
NM_001177842.2	NP_001171313.1	signal recognition particle receptor subunit alpha isoform 2
NM_003139.4	NP_003130.2	signal recognition particle receptor subunit alpha isoform 1

基因本体论

细胞组分

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in membrane	IDA IDA: 通过直接分析推断	22375059	GOA
part of signal recognition particle receptor complex	EXP EXP: 通过实验结果推断	16439358	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SRPRA 蛋白结构

SRP-alpha_N

SRP54_N

SRP54

0
100
200
300
400
500
600
638 a.a.

蛋白主名

其他名称

signal recognition particle receptor subunit alpha

DP-alpha

关联疾病

疾病名称

别名

Shwachman-Diamond Syndrome 1

Shwachman-Diamond Syndrome	Shwachman Syndrome
Shwachman-Bodian-Diamond Syndrome	Sds
Pancreatic Insufficiency And Bone Marrow Dysfunction	Shwachman-Bodian Syndrome
SDS1	Lipomatosis Of Pancreas, Congenital
Congenital Lipomatosis Of Pancreas	Shwachman-Diamond Type Metaphyseal Dysplasia
Metaphyseal Chondrodysplasia, Shwachman Type	Shwachman-Diamond-Oski Syndrome

Severe Congenital Neutropenia

Congenital Neutropenia	Neutropenia, Severe Congenital
Congenital Agranulocytosis	Infantile Genetic Agranulocytosis
Kostmann Disease	Kostmann'S Agranulocytosis
Kostmann'S Syndrome	Severe Infantile Genetic Neutropenia

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS13780	SRPRA Human Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Macaca mulatta	SRPRA	VGNC	VGNC:77885
Canis familiaris	SRPRA	VGNC	VGNC:53450
Rattus norvegicus	SRPRA	RGD	RGD:1311504
Mus musculus	SRPRA	MGD	MGI:1914648
Bos taurus	SRPRA	VGNC	VGNC:56282
Felis catus	SRPRA	VGNC	VGNC:104332

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

SRPRA - SRP receptor subunit alpha Gene

关于 SRPRA

功能概要

SRPRA 基因产物(2)

SRPRA 蛋白结构

关联疾病

直系同源

热门区域

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SRPRA - SRP receptor subunit alpha Gene

关于 SRPRA

功能概要

SRPRA 基因产物(2)

SRPRA 蛋白结构

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

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Q

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