2. Gene
  3. Plxnd1 - plexin D1 Gene

Plxnd1 - plexin D1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: b2b553Clo; b2b1863Clo; 6230425C21Rik

基因 ID: 67784 | 基因类型: protein coding

关于 Plxnd1

功能概要

Enables semaphorin receptor activity. Involved in several processes, including endothelial cell migration; semaphorin-plexin signaling pathway; and synapse assembly. Acts upstream of or within several processes, including circulatory system development; dichotomous subdivision of terminal units involved in salivary gland branching; and positive regulation of protein binding activity. Is integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; genitourinary system; liver; nervous system; and spleen. Used to study DiGeorge syndrome. Orthologous to human PLXND1 (plexin D1). [provided by Alliance of Genome Resources, Apr 2022]

Plxnd1 基因产物(1)

mRNA Protein Name
NM_026376.4 NP_080652.2 plexin-D1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15239958 MGI
enables semaphorin receptor activity IDA
IDA: 通过直接分析推断
17318185 MGI
enables semaphorin receptor activity IMP
IMP: 通过突变表型推断
25985275 MGI
enables semaphorin receptor activity IPI
IPI: 通过物理相互作用推断
15239958 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in angiogenesis IMP
IMP: 通过突变表型推断
18992737 MGI
acts upstream of or within aorta development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within branching involved in blood vessel morphogenesis IMP
IMP: 通过突变表型推断
15239958 MGI
acts upstream of or within cardiac septum development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within coronary vasculature development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within dichotomous subdivision of terminal units involved in salivary gland branching IDA
IDA: 通过直接分析推断
17626059 MGI
involved in endothelial cell migration IMP
IMP: 通过突变表型推断
18992737 MGI
acts upstream of or within kidney development IMP
IMP: 通过突变表型推断
27002738 MGI
involved in negative regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
25985275 MGI
acts upstream of or within outflow tract morphogenesis IMP
IMP: 通过突变表型推断
23918385 MGI
acts upstream of or within positive regulation of protein binding IDA
IDA: 通过直接分析推断
15239958 MGI
involved in regulation of angiogenesis IMP
IMP: 通过突变表型推断
17318185 MGI
involved in regulation of cell migration IMP
IMP: 通过突变表型推断
17318185 MGI
acts upstream of or within semaphorin-plexin signaling pathway IGI
IGI: 通过遗传相互作用推断
15239958 MGI
involved in semaphorin-plexin signaling pathway IGI
IGI: 通过遗传相互作用推断
25985275 MGI
involved in semaphorin-plexin signaling pathway IMP
IMP: 通过突变表型推断
17318185 MGI
involved in synapse assembly IMP
IMP: 通过突变表型推断
22179111 MGI
involved in synaptic target recognition IDA
IDA: 通过直接分析推断
22179111 MGI
involved in synaptic target recognition IMP
IMP: 通过突变表型推断
22179111 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
25985275 MGI
located in cell body IDA
IDA: 通过直接分析推断
25985275 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
22179111 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
22179111 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
17318185 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

plexin-D1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10756 PLXND1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20190 Plxnd1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26694 Plxnd1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Plxnd1 NCBI NCBI:23129
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