1. Gene
  2. Grhpr - glyoxylate and hydroxypyruvate reductase Gene

Grhpr - glyoxylate and hydroxypyruvate reductase Gene

种属: Rattus norvegicus

基因 ID: 680021 | 基因类型: protein coding

关于 Grhpr

功能概要

Enables carboxylic acid binding activity; nucleotide binding activity; and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Involved in dicarboxylic acid metabolic process. Located in cytosol. Human ortholog(s) of this gene implicated in primary hyperoxaluria and primary hyperoxaluria type 2. Orthologous to human GRHPR (glyoxylate and hydroxypyruvate reductase). [provided by Alliance of Genome Resources, Apr 2022]

Grhpr 基因产物(1)

mRNA Protein Name
NM_001113754.1 NP_001107226.1 glyoxylate reductase/hydroxypyruvate reductase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables NAD binding IDA
IDA: 通过直接分析推断
2689175 RGD
enables NADP binding IDA
IDA: 通过直接分析推断
2689175 RGD
enables carboxylic acid binding IPI
IPI: 通过物理相互作用推断
2689175 RGD
enables glyoxylate reductase (NADPH) activity IDA
IDA: 通过直接分析推断
2689175 RGD
enables hydroxypyruvate reductase (NADH) activity IDA
IDA: 通过直接分析推断
2689175 RGD
enables hydroxypyruvate reductase [NAD(P)H] activity IDA
IDA: 通过直接分析推断
2689175 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in dicarboxylic acid metabolic process IDA
IDA: 通过直接分析推断
2689175 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

glyoxylate reductase/hydroxypyruvate reductase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Grhpr NCBI NCBI:9380
Mus musculus Grhpr NCBI NCBI:76238