1. Gene
  2. Cacna1s - calcium voltage-gated channel subunit alpha1 S Gene

Cacna1s - calcium voltage-gated channel subunit alpha1 S Gene

种属: Rattus norvegicus

同用名: Cchl1a3; RGD1565743

基因 ID: 682930 | 基因类型: protein coding

关于 Cacna1s

功能概要

Enables high voltage-gated Calcium Channel activity. Involved in calcium ion transport. Located in dendritic spine head and sarcolemma. Part of voltage-gated Calcium Channel complex. Human ortholog(s) of this gene implicated in hypokalemic periodic paralysis and malignant hyperthermia. Orthologous to human CACNA1S (calcium voltage-gated channel subunit alpha1 S). [provided by Alliance of Genome Resources, Apr 2022]

Cacna1s 基因产物(1)

mRNA Protein Name
NM_053873.1 NP_446325.1 voltage-dependent L-type calcium channel subunit alpha-1S
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables high voltage-gated calcium channel activity IDA
IDA: 通过直接分析推断
7479909 RGD
enables voltage-gated calcium channel activity IDA
IDA: 通过直接分析推断
20101487 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in calcium ion transport IDA
IDA: 通过直接分析推断
7479909 RGD
involved in response to caloric restriction IEP
IEP: 通过表达模式推断
9742952 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendritic spine head IDA
IDA: 通过直接分析推断
24519419 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
21474431 RGD
part of voltage-gated calcium channel complex IDA
IDA: 通过直接分析推断
7479909 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

voltage-dependent L-type calcium channel subunit alpha-1S

ROB1

calcium channel, voltage-dependent, L type, alpha 1S subunit

voltage-gated calcium channel subunit alpha Cav1.1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cacna1s NCBI NCBI:779