2. Gene
  3. SYCP1 - synaptonemal complex protein 1 Gene

SYCP1 - synaptonemal complex protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：联会复合蛋白 1

种属: Homo sapiens

同用名: CT8; SCP1; SCP-1; HOM-TES-14

基因 ID: 6847 | 基因类型: protein coding

关于 SYCP1

Cytogenetic location: 1p13.2 Genomic coordinates (GRCh38): 1:114,854,088-114,995,370 (from NCBI)

This gene has 10 transcripts (splice variants) and 181 orthologues. Restricted expression toward testis (RPKM 18.8).

功能概要

启用双链 DNA 结合活性。参与蛋白质同源四聚化。预测位于联会复合体中。预计活跃于 central element；雄性生殖细胞核；和横丝。 [由基因组资源联盟提供，2022 年 4 月]

Enables double-stranded DNA binding activity. Involved in protein homotetramerization. Predicted to be located in synaptonemal complex. Predicted to be active in central element; male germ cell nucleus; and transverse filament. [provided by Alliance of Genome Resources, Apr 2022]

SYCP1 基因产物(3)

mRNA Protein Name
NM_001282541.2 NP_001269470.1 synaptonemal complex protein 1 isoform 1
NM_001282542.2 NP_001269471.1 synaptonemal complex protein 1 isoform 2
NM_003176.4 NP_003167.2 synaptonemal complex protein 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
29915389 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in protein homotetramerization IDA
IDA: 通过直接分析推断
29915389 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SYCP1 蛋白结构

SCP-1

SCP-1: Synaptonemal complex protein 1 (SCP-1) (28 - 792)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 976 a.a.
蛋白主名 其他名称

synaptonemal complex protein 1

cancer/testis antigen 8

关联疾病

疾病名称 别名
Male Infertility

Infertility, Male

Infertility Male

Male Sterility

Absolute Infertility
Testicular Cancer

Testis Cancer

Testicular Carcinoma

Testicular Neoplasms

Malignant Neoplasm Of Testis

Childhood Neoplasm Of The Testis

Neoplasm Of Testis

Pediatric Testicular Neoplasm

Testicular Tumor

Testis Neoplasm

Testicular Tumors

Testicular Neoplasm

Testicular Malignant Germ Cell Tumor

Childhood Testicular Neoplasm

Carcinoma Of The Testis

Cancer Of Testis

Malignant Neoplasm Of Testis, Nos

Malignant Neoplasm Of Testis, Unspecified

Malignant Tumour Of Testis

Testicle Cancer

Primary Malignant Neoplasm Of Testis
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
Infertility
Premature Menopause

Primary Ovarian Insufficiency

Premature Ovarian Failure

Hypergonadotropic Hypogonadism

Premature Ovarian Insufficiency

Menopause - Premature

Menopause Praecox

Menopause Premature

Menopause, Premature

Female Hypergonadotropic Hypogonadism

Hypergonadotrophic Ovarian Failure

Primary Female Hypogonadism

Pof - [Premature Ovarian Failure]

Ovarian Failure

Ovarian Secretion Suppression

Ovary Hyposecretion

Ovary Secretion Deficiency

Premature Menopause Nos
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14070 SYCP1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus SYCP1 VGNC VGNC:35508
Canis familiaris SYCP1 VGNC VGNC:47018
Mus musculus SYCP1 MGD MGI:105931
Macaca mulatta SYCP1 VGNC VGNC:78062
Felis catus SYCP1 VGNC VGNC:80371
Rattus norvegicus SYCP1 RGD RGD:3794
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