1. Gene
  2. Mtcl1 - microtubule crosslinking factor 1 Gene

Mtcl1 - microtubule crosslinking factor 1 Gene

种属: Mus musculus

同用名: Soga2; Ccdc165; Kiaa0802; t8219b25; mKIAA0802; D130071O13; 1110012J17Rik

基因 ID: 68617 | 基因类型: protein coding

关于 Mtcl1

功能概要

Enables microtubule binding activity and protein homodimerization activity. Involved in establishment or maintenance of epithelial cell apical/basal polarity; microtubule bundle formation; and positive regulation of protein targeting to membrane. Located in several cellular components, including apicolateral plasma membrane; cytoskeleton; and lateral plasma membrane. Is expressed in several structures, including alimentary system; cranial ganglion; limb segment; metanephros; and neural ectoderm. Orthologous to human MTCL1 (microtubule crosslinking factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Mtcl1 基因产物(2)

mRNA Protein Name
NM_001114098.2 NP_001107570.1 microtubule cross-linking factor 1 isoform 1
NM_172963.4 NP_766551.3 microtubule cross-linking factor 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables microtubule binding IDA
IDA: 通过直接分析推断
23902687 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
23902687 MGI
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
23902687 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in establishment or maintenance of epithelial cell apical/basal polarity IDA
IDA: 通过直接分析推断
23902687 MGI
involved in microtubule bundle formation IDA
IDA: 通过直接分析推断
23902687 MGI
involved in positive regulation of protein targeting to membrane IDA
IDA: 通过直接分析推断
23902687 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apicolateral plasma membrane IDA
IDA: 通过直接分析推断
23902687 MGI
located in cytoskeleton IDA
IDA: 通过直接分析推断
23902687 MGI
located in lateral plasma membrane IDA
IDA: 通过直接分析推断
23902687 MGI
located in microtubule bundle IDA
IDA: 通过直接分析推断
23902687 MGI
located in midbody IDA
IDA: 通过直接分析推断
23902687 MGI
located in spindle pole IDA
IDA: 通过直接分析推断
23902687 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

microtubule cross-linking factor 1

PAR-1-interacting protein

SOGA family member 2

coiled-coil domain-containing protein 165

protein SOGA2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mtcl1 NCBI NCBI:23255