2. Gene
  3. Suz12 - SUZ12 polycomb repressive complex 2 subunit Gene

Suz12 - SUZ12 polycomb repressive complex 2 subunit Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 688041 | 基因类型: protein coding

关于 Suz12

功能概要

Predicted to enable several functions, including nucleic acid binding activity; promoter-specific chromatin binding activity; and transcription corepressor binding activity. Involved in several processes, including histone H3-K27 trimethylation; negative regulation of macromolecule metabolic process; and response to retinoic acid. Predicted to be located in nuclear body; nucleolus; and sex chromatin. Predicted to be part of nucleus; protein-DNA complex; and ribonucleoprotein complex. Biomarker of spina bifida. Orthologous to human SUZ12 (SUZ12 polycomb repressive complex 2 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Suz12 基因产物(3)

mRNA Protein Name
XM_039087644.1 XP_038943572.1 polycomb protein SUZ12 isoform X1
XM_039087645.1 XP_038943573.1 polycomb protein SUZ12 isoform X2
XM_039087646.1 XP_038943574.1 polycomb protein SUZ12 isoform X3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23879974 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of chemokine production IMP
IMP: 通过突变表型推断
23192652 RGD
involved in negative regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
23192652 RGD
involved in negative regulation of protein modification process IMP
IMP: 通过突变表型推断
23192652 RGD
involved in protein modification process IMP
IMP: 通过突变表型推断
23192652 RGD
involved in response to retinoic acid IEP
IEP: 通过表达模式推断
20515739 RGD
involved in spinal cord development IEP
IEP: 通过表达模式推断
20515739 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

polycomb protein SUZ12

相关产品

Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101512 A-395 Inhibitor 99.12% 否
HY-W014099 Boc-NH-C4-acid 99.85% 否
HY-158239 MS181 Inhibitor 98.36% 否
HY-157164 PROTAC EZH2 Degrader-2 Degrader 99.78% 否
HY-130638 (S,R,S)-AHPC-O-Ph-PEG1-NH-Boc / 否
HY-101512D rel-A-395 hydrochloride Inhibitor / 否
HY-130637 Boc-NH-PEG1-Ph-O-CH2COOH / 否
HY-174372 EZH2-IN-23 Inhibitor / 否
HY-RS14053 SUZ12 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17149 Suz12 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23598 Suz12 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Suz12 NCBI NCBI:23512
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