1. Gene
  2. Nexn - nexilin Gene

Nexn - nexilin Gene

种属: Mus musculus

同用名: NELIN; 1110046H09Rik

基因 ID: 68810 | 基因类型: protein coding

关于 Nexn

功能概要

Predicted to enable actin filament binding activity and cell-cell adhesion mediator activity. Predicted to be a structural constituent of muscle. Acts upstream of or within response to bacterium. Predicted to be located in Z disc; actin cytoskeleton; and focal adhesion. Predicted to be active in axon and plasma membrane. Is expressed in diaphragm; gut; head mesenchyme; heart; and vertebral axis musculature. Used to study dilated cardiomyopathy 1CC and hypertrophic cardiomyopathy 20. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1CC and hypertrophic cardiomyopathy 20. Orthologous to human NEXN (nexilin F-actin binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Nexn 基因产物(2)

mRNA Protein Name
NM_001357206.2 NP_001344135.1 nexilin isoform 1
NM_199465.4 NP_955759.2 nexilin isoform 2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

nexilin

F-actin-binding protein

nF actin binding protein

nexilin alpha

nexilin beta

nexilin gamma

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nexn NCBI NCBI:91624