2. Gene
  3. Cdkal1 - CDK5 regulatory subunit associated protein 1-like 1 Gene

Cdkal1 - CDK5 regulatory subunit associated protein 1-like 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 1190005B03Rik; 6620401C13Rik

基因 ID: 68916 | 基因类型: protein coding

关于 Cdkal1

功能概要

Enables N6-threonylcarbomyladenosine methylthiotransferase activity. Acts upstream of or within maintenance of translational fidelity and tRNA methylthiolation. Located in rough endoplasmic reticulum. Is expressed in olfactory epithelium and testis. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in diabetes mellitus; gestational diabetes; and type 2 diabetes mellitus. Orthologous to human CDKAL1 (CDK5 regulatory subunit associated protein 1 like 1). [provided by Alliance of Genome Resources, Apr 2022]

Cdkal1 基因产物(2)

mRNA Protein Name
NM_001308486.1 NP_001295415.1 threonylcarbamoyladenosine tRNA methylthiotransferase isoform 2
NM_144536.3 NP_653119.1 threonylcarbamoyladenosine tRNA methylthiotransferase isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables N6-threonylcarbomyladenosine methylthiotransferase activity IMP
IMP: 通过突变表型推断
21841312 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within maintenance of translational fidelity IMP
IMP: 通过突变表型推断
21841312 MGI
acts upstream of or within tRNA methylthiolation IMP
IMP: 通过突变表型推断
21841312 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
21151568 MGI
located in rough endoplasmic reticulum IDA
IDA: 通过直接分析推断
21841312 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

threonylcarbamoyladenosine tRNA methylthiotransferase

tRNA-t(6)A37 methylthiotransferase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02404 CDKAL1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21102 Cdkal1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27621 Cdkal1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cdkal1 NCBI NCBI:54901
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