TEAD4 - TEA domain transcription factor 4 Gene

中文名称：TEA 域转录因子 4

种属: Homo sapiens

同用名: TEF3; RTEF1; TEF-3; EFTR-2; TEFR-1; TCF13L1; hRTEF-1B

关于 TEAD4

功能概要

该基因产物是转录因子转录增强因子 (TEF) 家族的成员，其中包含 TEA/ATTS DNA 结合域。它优先在骨骼肌中表达，并与肌肉特异性基因启动子中发现的 M-CAT 调节元件结合，以指导其基因表达。编码不同同种型的可变剪接转录物，其中一些通过使用非 AUG (UUG) 起始密码子翻译，已经对该基因进行了描述。[RefSeq 提供，2008 年 7 月]

This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene. [provided by RefSeq, Jul 2008]