2. Gene
  3. Megf10 - multiple EGF-like-domains 10 Gene

Megf10 - multiple EGF-like-domains 10 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gm331; 3000002B06Rik

基因 ID: 70417 | 基因类型: protein coding

关于 Megf10

功能概要

Enables Notch binding activity. Involved in several processes, including myoblast migration; skeletal muscle satellite cell differentiation; and skeletal muscle satellite cell proliferation. Acts upstream of or within apoptotic process involved in development; engulfment of apoptotic cell; and recognition of apoptotic cell. Located in phagocytic cup. Is expressed in several structures, including cerebellum; dorsal root ganglion; retina layer; skeletal muscle tissue; and testis. Human ortholog(s) of this gene implicated in early-onset myopathy-areflexia-respiratory distress-dysphagia syndrome. Orthologous to human MEGF10 (multiple EGF like domains 10). [provided by Alliance of Genome Resources, Apr 2022]

Megf10 基因产物(1)

mRNA Protein Name
NM_001001979.2 NP_001001979.1 multiple epidermal growth factor-like domains protein 10 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Notch binding IPI
IPI: 通过物理相互作用推断
28498977 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within apoptotic process involved in development IMP
IMP: 通过突变表型推断
27170117 MGI
acts upstream of or within engulfment of apoptotic cell IMP
IMP: 通过突变表型推断
27170117 MGI
involved in myoblast development IMP
IMP: 通过突变表型推断
31267131 MGI
involved in myoblast migration IMP
IMP: 通过突变表型推断
28498977 MGI
involved in positive regulation of myoblast proliferation IMP
IMP: 通过突变表型推断
31267131 MGI
acts upstream of or within recognition of apoptotic cell IDA
IDA: 通过直接分析推断
19915564 MGI
acts upstream of or within recognition of apoptotic cell IMP
IMP: 通过突变表型推断
19915564 MGI
involved in skeletal muscle satellite cell activation IMP
IMP: 通过突变表型推断
18056409 MGI
involved in skeletal muscle satellite cell differentiation IMP
IMP: 通过突变表型推断
18056409 MGI
involved in skeletal muscle satellite cell proliferation IDA
IDA: 通过直接分析推断
18056409 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in phagocytic cup IDA
IDA: 通过直接分析推断
19915564 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
17643423 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

multiple epidermal growth factor-like domains protein 10

multiple EGF-like domains protein 10

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08314 MEGF10 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18007 Megf10 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24480 Megf10 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Megf10 NCBI NCBI:84466
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