1. Gene
  2. Inf2 - inverted formin, FH2 and WH2 domain containing Gene

Inf2 - inverted formin, FH2 and WH2 domain containing Gene

种属: Mus musculus

同用名: EG629699; 2610204M08Rik

基因 ID: 70435 | 基因类型: protein coding

关于 Inf2

功能概要

Predicted to enable actin binding activity and small GTPase binding activity. Acts upstream of or within regulation of cellular component size. Predicted to be located in perinuclear region of cytoplasm. Is expressed in several structures, including adipose tissue; alimentary system; hemolymphoid system; nervous system; and reproductive system. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate E and focal segmental glomerulosclerosis 5. Orthologous to human INF2 (inverted formin 2). [provided by Alliance of Genome Resources, Apr 2022]

Inf2 基因产物(2)

mRNA Protein Name
NM_001374199.1 NP_001361128.1 inverted formin-2 isoform 2
NM_198411.2 NP_940803.2 inverted formin-2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21278336 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within actin nucleation IDA
IDA: 通过直接分析推断
21278336 MGI
acts upstream of or within gene expression IDA
IDA: 通过直接分析推断
21278336 MGI
acts upstream of or within regulation of cellular component size IMP
IMP: 通过突变表型推断
23349293 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

inverted formin-2

formin, inverted

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Inf2 NCBI NCBI:64423
Macaca fascicularis Inf2 NCBI NCBI:102140963