2. Gene
  3. Unc13d - unc-13 homolog D Gene

Unc13d - unc-13 homolog D Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Jinx; Munc13-4; mFLJ00067; 2610108D09Rik

基因 ID: 70450 | 基因类型: protein coding

关于 Unc13d

功能概要

Predicted to enable small GTPase binding activity. Involved in platelet dense granule organization; positive regulation of substrate adhesion-dependent cell spreading; and vasculature development. Acts upstream of or within several processes, including defense response to Other organism; germinal center formation; and granuloma formation. Predicted to be located in cytosol; lysosome; and secretory vesicle. Used to study familial hemophagocytic lymphohistiocytosis 3. Human ortholog(s) of this gene implicated in familial hemophagocytic lymphohistiocytosis 3. Orthologous to human UNC13D (unc-13 homolog D). [provided by Alliance of Genome Resources, Apr 2022]

Unc13d 基因产物(1)

mRNA Protein Name
NM_001009573.2 NP_001009573.2 protein unc-13 homolog D
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18354201 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within defense response to virus IMP
IMP: 通过突变表型推断
17420270 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
17420270 MGI
acts upstream of or within germinal center formation IMP
IMP: 通过突变表型推断
17420270 MGI
acts upstream of or within granuloma formation IMP
IMP: 通过突变表型推断
17420270 MGI
acts upstream of or within natural killer cell degranulation IMP
IMP: 通过突变表型推断
17420270 MGI
acts upstream of or within phagocytosis IMP
IMP: 通过突变表型推断
17420270 MGI
involved in positive regulation of substrate adhesion-dependent cell spreading IMP
IMP: 通过突变表型推断
22589474 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein unc-13 homolog D

likely ortholog of H. sapiens unc-13 homolog D (UNC13D)

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15467 UNC13D Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21975 Unc13d Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Unc13d NCBI NCBI:201294
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