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  2. Mutyh - mutY DNA glycosylase Gene

Mutyh - mutY DNA glycosylase Gene

种属: Mus musculus

同用名: Myh; Mutyha; Mutyhb; Mutyhc; Mutyhbeta; Mutyhalpha; 5730495A01Rik

基因 ID: 70603 | 基因类型: protein coding

关于 Mutyh

功能概要

Predicted to enable DNA N-glycosylase activity; DNA binding activity; and MutSalpha complex binding activity. Involved in negative regulation of necroptotic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in familial adenomatous polyposis; familial adenomatous polyposis 2; and stomach carcinoma. Orthologous to human MUTYH (mutY DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]

Mutyh 基因产物(3)

mRNA Protein Name
NM_001159581.1 NP_001153053.1 adenine DNA glycosylase isoform a
NM_001316747.1 NP_001303676.1 adenine DNA glycosylase isoform b
NM_133250.2 NP_573513.2 adenine DNA glycosylase isoform a
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of necroptotic process IMP
IMP: 通过突变表型推断
28059467 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

adenine DNA glycosylase

a/G-specific adenine DNA glycosylase

mMYH

mutY homolog alpha

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mutyh NCBI NCBI:4595