2. Gene
  3. Ubr5 - ubiquitin protein ligase E3 component n-recognin 5 Gene

Ubr5 - ubiquitin protein ligase E3 component n-recognin 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Edd; Edd1

基因 ID: 70790 | 基因类型: protein coding

关于 Ubr5

功能概要

Predicted to enable protein domain specific binding activity and ubiquitin-ubiquitin Ligase activity. Acts upstream of or within negative regulation of interleukin-17 production and regulation of protein stability. Predicted to be located in cytosol; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Is expressed in cranial ganglion; nervous system; sensory organ; submandibular gland primordium; and vibrissa. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Orthologous to human UBR5 (ubiquitin protein Ligase E3 component n-recognin 5). [provided by Alliance of Genome Resources, Apr 2022]

Ubr5 基因产物(2)

mRNA Protein Name
NM_001081359.3 NP_001074828.2 E3 ubiquitin-protein ligase UBR5 isoform 1
NM_001112721.2 NP_001106192.1 E3 ubiquitin-protein ligase UBR5 isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25470037 MGI
enables ubiquitin protein ligase activity IDA
IDA: 通过直接分析推断
19008229 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of interleukin-17 production IGI
IGI: 通过遗传相互作用推断
25470037 MGI
involved in negative regulation of smoothened signaling pathway IMP
IMP: 通过突变表型推断
27299863 MGI
acts upstream of or within regulation of protein stability IMP
IMP: 通过突变表型推断
25470037 MGI
involved in ubiquitin-dependent protein catabolic process via the N-end rule pathway IDA
IDA: 通过直接分析推断
16055722 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase UBR5

E3 ubiquitin-protein ligase, HECT domain-containing 1

HECT-type E3 ubiquitin transferase UBR5

extraembryonic development

hyperplastic discs protein homolog

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15390 UBR5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18504 Ubr5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24986 Ubr5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ubr5 NCBI NCBI:51366
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