2. Gene
  3. TNR - tenascin R Gene

TNR - tenascin R Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：生腱蛋白 R

种属: Homo sapiens

同用名: TN-R; NEDSTO

基因 ID: 7143 | 基因类型: protein coding

关于 TNR

Cytogenetic location: 1q25.1 Genomic coordinates (GRCh38): 1:175,315,194-175,743,595 (from NCBI)

This gene has 3 transcripts (splice variants), 209 orthologues, 25 paralogues and is associated with 1 phenotype. Restricted expression toward brain (RPKM 22.5).

功能概要

该基因编码细胞外基质糖蛋白生腱蛋白家族的成员。编码的蛋白质仅限于中枢神经系统。该蛋白质可能在神经突生长、神经细胞粘附和钠通道功能调节中发挥作用。它是神经元周围网的组成部分。[RefSeq 提供，2013 年 8 月]

This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The encoded protein is restricted to the central nervous system. The protein may play a role in neurite outgrowth, neural cell adhesion and modulation of Sodium Channel function. It is a constituent of perineuronal nets. [provided by RefSeq, Aug 2013]

TNR 基因产物(2)

mRNA Protein Name
NM_001328635.2 NP_001315564.1 tenascin-R isoform 2
NM_003285.3 NP_003276.3 tenascin-R isoform 1 precursor

TNR 蛋白结构

EGF_2

EGF_2: EGF-like domain (204 - 230)

EGF_2

EGF_2: EGF-like domain (300 - 323)

fn3

fn3: Fibronectin type III domain (328 - 399)

fn3

fn3: Fibronectin type III domain (416 - 495)

fn3

fn3: Fibronectin type III domain (507 - 582)

fn3

fn3: Fibronectin type III domain (595 - 672)

fn3

fn3: Fibronectin type III domain (688 - 764)

fn3

fn3: Fibronectin type III domain (776 - 850)

fn3

fn3: Fibronectin type III domain (865 - 942)

fn3

fn3: Fibronectin type III domain (955 - 1027)

fn3

fn3: Fibronectin type III domain (1042 - 1118)

Fibrinogen_C

Fibrinogen_C: Fibrinogen beta and gamma chains, C-terminal globular domain (1135 - 1343)

  • 0
  • 300
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  • 900
  • 1200
  • 1358 a.a.
蛋白主名 其他名称

tenascin-R

janusin

关联疾病

疾病名称 别名
Neurodevelopmental Disorder, Nonprogressive, With Spasticity And Transient Opisthotonus

NEDSTO

Neurodevelopmental Disorder, Non-Progressive, With Spasticity And Transient Opisthotonus

Non-Progressive Neurodevelopmental Disorder With Spasticity And Transient Opisthotonus
Spasticity
Osteochondritis Dissecans

Osteochondritis

Ocd

Konig Disease
Ehlers-Danlos Syndrome

Eds

Cutis Hyperelastica

Elastic Skin

Ehlers-Danlos Syndromes

Ed Syndrome

Ehlers Danlos Syndrome

Ehlers Danlos Disease

Eds - [Ehlers-Danlos Syndrome]
Diamond-Blackfan Anemia 1

Aase Syndrome

DBA1

Erythrogenesis Imperfecta

Aase-Smith Syndrome Ii

Dba

Blackfan-Diamond Syndrome

Bds

Anemia, Congenital Hypoplastic, Of Blackfan And Diamond

Anemia, Congenital Erythroid Hypoplastic

Red Cell Aplasia, Pure, Hereditary

Aregenerative Anemia, Chronic Congenital

Rps19-Related Diamond-Blackfan Anemia

Chronic Congenital Aregenerative Anemia

Congenital Erythroid Hypoplastic Anemia

Congenital Hypoplastic Anemia Of Blackfan And Diamond

Pure Hereditary Red Cell Aplasia

Anemia, Diamond-Blackfan, Type 1

Anemia, Diamond-Blackfan

Aase Smith Syndrome 2

Familial Hypoplastic Anaemia With Malformations

Constitutional Pure Red Cell Aplasia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14862 TNR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18902 Tnr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25393 Tnr Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris TNR VGNC VGNC:47697
Mus musculus TNR MGD MGI:99516
Macaca mulatta TNR VGNC VGNC:78609
Rattus norvegicus TNR RGD RGD:3886
Bos taurus TNR VGNC VGNC:36202
Felis catus TNR VGNC VGNC:66433
Others TNR NCBI
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