Mad2l2 - MAD2 mitotic arrest deficient-like 2 Gene

种属: Mus musculus

同用名: REV7; MAD2B; repro22; G1-453-4; 2310033C13Rik

关于 Mad2l2

功能概要

Predicted to enable JUN kinase binding activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in several processes, including negative regulation of cell-cell adhesion mediated by cadherin; regulation of nucleobase-containing compound metabolic process; and regulation of protein metabolic process. Predicted to act upstream of or within DNA repair and cell division. Predicted to be located in cytosol; nucleolus; and spindle. Predicted to be part of anaphase-promoting complex and zeta DNA Polymerase complex. Is expressed in several structures, including brain; ganglia; genitourinary system; intestine; and olfactory epithelium. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group V. Orthologous to human MAD2L2 (mitotic arrest deficient 2 like 2). [provided by Alliance of Genome Resources, Apr 2022]