1. Gene
  2. Slc39a4 - solute carrier family 39 (zinc transporter), member 4 Gene

Slc39a4 - solute carrier family 39 (zinc transporter), member 4 Gene

种属: Mus musculus

同用名: ZIP4; AWMS2; 1600025H15Rik

基因 ID: 72027 | 基因类型: protein coding

关于 Slc39a4

功能概要

Enables zinc ion transmembrane transporter activity. Acts upstream of or within cellular response to zinc ion starvation; cellular zinc ion homeostasis; and zinc ion transport. Located in apical plasma membrane and endosome. Is expressed in several structures, including alimentary system; early embryo; extraembryonic component; genitourinary system; and integumental system. Used to study acrodermatitis enteropathica. Human ortholog(s) of this gene implicated in acrodermatitis enteropathica. Orthologous to human SLC39A4 (solute carrier family 39 member 4). [provided by Alliance of Genome Resources, Apr 2022]

Slc39a4 基因产物(1)

mRNA Protein Name
NM_028064.3 NP_082340.1 zinc transporter ZIP4 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IDA
IDA: 通过直接分析推断
30593504 MGI
enables zinc ion transmembrane transporter activity IDA
IDA: 通过直接分析推断
14612438 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to zinc ion starvation IDA
IDA: 通过直接分析推断
15358787 MGI
involved in intracellular zinc ion homeostasis IDA
IDA: 通过直接分析推断
12801924 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
12801924 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
14612438 MGI
located in recycling endosome membrane IDA
IDA: 通过直接分析推断
14612438 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

zinc transporter ZIP4

activated in W/Wv mouse stomach 2

zrt- and Irt-like protein 4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc39a4 NCBI NCBI:55630