2. Gene
  3. Aplf - aprataxin and PNKP like factor Gene

Aplf - aprataxin and PNKP like factor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 2010301N04Rik

基因 ID: 72103 | 基因类型: protein coding

关于 Aplf

功能概要

Predicted to enable DNA-(apurinic or apyrimidinic site) Endonuclease activity; nuclease activity; and nucleotide binding activity. Acts upstream of or within double-strand break repair and regulation of isotype switching. Predicted to be located in nucleoplasm. Predicted to be active in nucleus and site of double-strand break. Orthologous to human APLF (aprataxin and PNKP like factor). [provided by Alliance of Genome Resources, Apr 2022]

Aplf 基因产物(3)

mRNA Protein Name
NM_001170489.1 NP_001163960.1 aprataxin and PNK-like factor isoform 1
NM_001372332.1 NP_001359261.1 aprataxin and PNK-like factor isoform 3
NM_024251.4 NP_077213.2 aprataxin and PNK-like factor isoform 2
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within double-strand break repair IMP
IMP: 通过突变表型推断
21211721 MGI
involved in embryo implantation IMP
IMP: 通过突变表型推断
33277378 MGI
involved in regulation of epithelial to mesenchymal transition IMP
IMP: 通过突变表型推断
33277378 MGI
acts upstream of or within regulation of isotype switching IMP
IMP: 通过突变表型推断
21211721 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytosol IDA
IDA: 通过直接分析推断
33277378 MGI
is active in nucleus IDA
IDA: 通过直接分析推断
33277378 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

aprataxin and PNK-like factor

apurinic-apyrimidinic endonuclease APLF

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00821 APLF Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22105 Aplf Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28626 Aplf Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aplf NCBI NCBI:200558
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