2. Gene
  3. Lrpprc - leucine-rich PPR-motif containing Gene

Lrpprc - leucine-rich PPR-motif containing Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Lsfc; Gp130; Lrp130; 3110001K13Rik

基因 ID: 72416 | 基因类型: protein coding

关于 Lrpprc

功能概要

Enables RNA binding activity and single-stranded DNA binding activity. Acts upstream of or within negative regulation of mitochondrial RNA catabolic process and regulation of mitochondrial translation. Located in mitochondrion and nucleus. Part of ribonucleoprotein complex. Is expressed in several structures, including brain; genitourinary system; heart; liver; and skeletal muscle. Human ortholog(s) of this gene implicated in French Canadian Leigh disease and Leigh disease. Orthologous to human LRPPRC (leucine rich pentatricopeptide repeat containing). [provided by Alliance of Genome Resources, Apr 2022]

Lrpprc 基因产物(1)

mRNA Protein Name
NM_028233.2 NP_082509.2 leucine-rich PPR motif-containing protein, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA binding IDA
IDA: 通过直接分析推断
21880015 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17050673 MGI
enables single-stranded DNA binding IDA
IDA: 通过直接分析推断
12071956 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of mitochondrial RNA catabolic process IMP
IMP: 通过突变表型推断
21880015 MGI
acts upstream of or within negative regulation of mitochondrial RNA catabolic process IGI
IGI: 通过遗传相互作用推断
22045337 MGI
acts upstream of or within negative regulation of mitochondrial RNA catabolic process IMP
IMP: 通过突变表型推断
21880015 MGI
acts upstream of or within regulation of mitochondrial translation IMP
IMP: 通过突变表型推断
22045337 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
12071956 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
14651853 MGI
located in nucleus IDA
IDA: 通过直接分析推断
12071956 MGI
part of ribonucleoprotein complex IDA
IDA: 通过直接分析推断
22045337 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

leucine-rich PPR motif-containing protein, mitochondrial

130 kDa leucine-rich protein

leucine rich protein LRP130

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-168519 STAT3-IN-36 Inhibitor / 否
HY-RS07804 LRPPRC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20563 Lrpprc Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27072 Lrpprc Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lrpprc NCBI NCBI:10128
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