TBC1D3 - TBC1 domain family member 3 Gene

中文名称：TBC1 域家族成员 3

种属: Homo sapiens

同用名: PRC17; TBC1D3A; TBC1D3C; TBC1D3D; TBC1D3F; TBC1D3L

基因 ID: 729873 | 基因类型: protein coding

关于 TBC1D3

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:38,181,659-38,192,555 (from NCBI)

This gene has 1 transcript (splice variant), 21 orthologues and 45 paralogues. Broad expression in testis (RPKM 25.9), skin (RPKM 14.0) and 24 other tissues.

功能概要

预测启用 GTPase 激活剂活动。预计参与 GTPase 活性的激活和细胞内蛋白质转运。预测位于早期内体膜。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity and intracellular protein transport. Predicted to be located in early endosome membrane. [provided by Alliance of Genome Resources, Apr 2022]

TBC1D3 基因产物(1)

mRNA	Protein	Name
NM_001123391.4	NP_001116863.3	TBC1 domain family member 3

基因本体论

生物过程

生物过程 GO 注释	逻辑证据	参考文献	来源
NOT involved in regulation of cilium assembly	IMP IMP: 通过突变表型推断	17646400	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TBC1D3 蛋白结构

RabGAP-TBC

0
100
200
300
400
500
593 a.a.

蛋白主名

其他名称

TBC1 domain family member 3

Rab GTPase-activating protein PRC17

关联疾病

疾病名称

别名

Prostate Cancer

Prostate Carcinoma	Prostate Cancer, Familial
Prostate Neoplasm	Prostate Cancer, Somatic
Prostate Cancer, Susceptibility To	Prostatic Cancer
Prostatic Neoplasms	Hereditary Prostate Cancer
Prostatic Neoplasm	Cancer Of Prostate
Carcinoma Of Prostate	Familial Prostate Cancer
Familial Prostate Carcinoma	Malignant Tumor Of Prostate
Malignant Neoplasm Of Prostate	Prostate Cancer, Familial, Susceptibility To
Malignant Tumor Of The Prostate	Ngp - New Growth Of Prostate
Tumor Of The Prostate	Prostate Cancer, Hereditary
Cancer Of The Prostate	Malignant Neoplasm Of The Prostate
Prostatic Carcinoma	PC
Prca	Cancer, Prostate
Malignant Prostatic Tumour	Malignant Tumour Of Prostate
Primary Prostate Cancer	Primary Malignant Neoplasm Of Prostate
Prostate Gland Cancer

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase

生物活性分子 (2)

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS14241	TBC1D3 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS14243	TBC1D3B Human Pre-designed siRNA Set A	Pre-designed Set	/	否

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