1. Gene
  2. Parn - poly(A)-specific ribonuclease (deadenylation nuclease) Gene

Parn - poly(A)-specific ribonuclease (deadenylation nuclease) Gene

种属: Mus musculus

同用名: DAN; 1200003I18Rik

基因 ID: 74108 | 基因类型: protein coding

关于 Parn

功能概要

Predicted to enable several functions, including cation binding activity; poly(A)-specific ribonuclease activity; and protein kinase binding activity. Acts upstream of or within nuclear-transcribed mRNA poly(A) tail shortening. Predicted to be located in nuclear speck and nucleolus. Predicted to be active in cytoplasm. Is expressed in bladder; male associated reproductive structure; testis; ureter; and urethra of male. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 6. Orthologous to human PARN (poly(A)-specific ribonuclease). [provided by Alliance of Genome Resources, Apr 2022]

Parn 基因产物(3)

mRNA Protein Name
NM_001358452.1 NP_001345381.1 poly(A)-specific ribonuclease PARN isoform 2
NM_001358453.1 NP_001345382.1 poly(A)-specific ribonuclease PARN isoform 3
NM_028761.3 NP_083037.1 poly(A)-specific ribonuclease PARN isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18337750 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within nuclear-transcribed mRNA poly(A) tail shortening IDA
IDA: 通过直接分析推断
18337750 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

poly(A)-specific ribonuclease PARN

polyadenylate-specific ribonuclease

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Parn NCBI NCBI:5073