2. Gene
  3. Lonp1 - lon peptidase 1, mitochondrial Gene

Lonp1 - lon peptidase 1, mitochondrial Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: LON; Prss15; 1200017E13Rik

基因 ID: 74142 | 基因类型: protein coding

关于 Lonp1

功能概要

Enables ATP hydrolysis activity; ATP-dependent peptidase activity; and DNA binding activity. Acts upstream of or within proteolysis. Located in mitochondrion. Is expressed in several structures, including adrenal medulla; alimentary system; genitourinary system; liver; and lung. Human ortholog(s) of this gene implicated in CODAS syndrome. Orthologous to human LONP1 (lon peptidase 1, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

Lonp1 基因产物(1)

mRNA Protein Name
NM_028782.2 NP_083058.2 lon protease homolog, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP hydrolysis activity IDA
IDA: 通过直接分析推断
12657466 MGI
enables ATP-dependent peptidase activity IDA
IDA: 通过直接分析推断
12657466 MGI
enables PH domain binding IPI
IPI: 通过物理相互作用推断
9813005 MGI
enables insulin receptor substrate binding IPI
IPI: 通过物理相互作用推断
9813005 MGI
NOT enables mitochondrial promoter sequence-specific DNA binding IDA
IDA: 通过直接分析推断
12657466 MGI
enables mitochondrial promoter sequence-specific DNA binding IDA
IDA: 通过直接分析推断
12657466 MGI
enables single-stranded DNA binding IDA
IDA: 通过直接分析推断
12657466 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
9813005 MGI
acts upstream of or within proteolysis IDA
IDA: 通过直接分析推断
12657466 MGI
acts upstream of or within regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
9813005 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
12657466 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lon protease homolog, mitochondrial

LONP

lon protease-like protein

mitochondrial ATP-dependent protease Lon

protease, serine, 15

serine protease 15

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-153034 LONP1-IN-2 / 否
HY-158412 BT317 99.81% 否
HY-RS07734 LONP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18289 Lonp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24767 Lonp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lonp1 NCBI NCBI:9361
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