1. Gene
  2. Rptor - regulatory associated protein of MTOR, complex 1 Gene

Rptor - regulatory associated protein of MTOR, complex 1 Gene

种属: Mus musculus

同用名: Rap; Raptor; mKIAA1303; 4932417H02Rik

基因 ID: 74370 | 基因类型: protein coding

关于 Rptor

功能概要

This gene encodes a subunit of mammalian target of rapamycin complex 1 (mTORC1), a component of the mTOR signaling pathway, which regulates cell growth in response to nutrient and energy levels. The encoded protein may regulate the assembly, localization, and substrate binding of the mTORC1 complex. Homozygous knockout mice for this gene exhibit embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Rptor 基因产物(2)

mRNA Protein Name
NM_001306081.1 NP_001293010.1 regulatory-associated protein of mTOR isoform 2
NM_028898.3 NP_083174.2 regulatory-associated protein of mTOR isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18046414 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in TORC1 signaling IMP
IMP: 通过突变表型推断
27879318 MGI
involved in negative regulation of insulin secretion IMP
IMP: 通过突变表型推断
23092880 MGI
involved in positive regulation of odontoblast differentiation IMP
IMP: 通过突变表型推断
30984011 MGI
involved in positive regulation of osteoclast differentiation IMP
IMP: 通过突变表型推断
27879318 MGI
involved in regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
23092880 MGI
involved in response to xenobiotic stimulus IMP
IMP: 通过突变表型推断
33495318 MGI
involved in social behavior IMP
IMP: 通过突变表型推断
33495318 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

regulatory-associated protein of mTOR

p150 target of rapamycin (TOR)-scaffold protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rptor NCBI NCBI:57521