1. Gene
  2. Dhcr24 - 24-dehydrocholesterol reductase Gene

Dhcr24 - 24-dehydrocholesterol reductase Gene

种属: Mus musculus

同用名: mKIAA0018; 2310076D10Rik; 5830417J06Rik

基因 ID: 74754 | 基因类型: protein coding

关于 Dhcr24

功能概要

Predicted to enable enzyme binding activity; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; and peptide antigen binding activity. Involved in skin development. Acts upstream of or within several processes, including amyloid precursor protein catabolic process; Cholesterol biosynthetic process; and plasminogen activation. Predicted to be located in several cellular components, including cytoskeleton; cytosol; and endoplasmic reticulum. Predicted to be active in cytoplasm and membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system ganglion; and sensory organ. Human ortholog(s) of this gene implicated in lipid metabolism disorder. Orthologous to human DHCR24 (24-dehydrocholesterol reductase). [provided by Alliance of Genome Resources, Apr 2022]

Dhcr24 基因产物(1)

mRNA Protein Name
NM_053272.3 NP_444502.2 delta(24)-sterol reductase precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within amyloid precursor protein catabolic process IMP
IMP: 通过突变表型推断
16407971 MGI
acts upstream of or within cholesterol biosynthetic process IMP
IMP: 通过突变表型推断
14684813 MGI
involved in cholesterol biosynthetic process IMP
IMP: 通过突变表型推断
14684813 MGI
acts upstream of or within cholesterol metabolic process IMP
IMP: 通过突变表型推断
16407971 MGI
acts upstream of or within male genitalia development IMP
IMP: 通过突变表型推断
14684813 MGI
acts upstream of or within membrane organization IMP
IMP: 通过突变表型推断
16407971 MGI
acts upstream of or within plasminogen activation IMP
IMP: 通过突变表型推断
16407971 MGI
acts upstream of or within protein localization IMP
IMP: 通过突变表型推断
16407971 MGI
involved in skin development IMP
IMP: 通过突变表型推断
16410790 MGI
acts upstream of or within sterol metabolic process IMP
IMP: 通过突变表型推断
14684813 MGI
acts upstream of or within tissue development IMP
IMP: 通过突变表型推断
14684813 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

delta(24)-sterol reductase

3-beta-hydroxysterol delta-24-reductase

seladin-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dhcr24 NCBI NCBI:1718