2. Gene
  3. Cul5 - cullin 5 Gene

Cul5 - cullin 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: VACM1; VACM-1; 4921514I20Rik; 8430423K24Rik; C030032G03Rik; C330021I08Rik

基因 ID: 75717 | 基因类型: protein coding

关于 Cul5

功能概要

Predicted to enable ubiquitin protein Ligase binding activity and ubiquitin-protein transferase activity. Acts upstream of or within cerebral cortex radially oriented cell migration; protein ubiquitination; and radial glia guided migration of Purkinje cell. Predicted to be located in several cellular components, including nucleus; plasma membrane; and site of DNA damage. Predicted to be part of Cul5-RING ubiquitin Ligase complex and SCF ubiquitin Ligase complex. Is expressed in several structures, including brain; eye; genitourinary system; gut; and limb bud. Orthologous to human CUL5 (cullin 5). [provided by Alliance of Genome Resources, Apr 2022]

Cul5 基因产物(2)

mRNA Protein Name
NM_001161618.2 NP_001155090.2 cullin-5 isoform 2
NM_027807.4 NP_082083.3 cullin-5 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15601820 MGI
enables ubiquitin ligase complex scaffold activity IMP
IMP: 通过突变表型推断
17974915 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cerebral cortex radially oriented cell migration IMP
IMP: 通过突变表型推断
24210661 MGI
involved in proteasome-mediated ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
17974915 MGI
acts upstream of or within protein ubiquitination IGI
IGI: 通过遗传相互作用推断
24210661 MGI
acts upstream of or within radial glia guided migration of Purkinje cell IMP
IMP: 通过突变表型推断
24210661 MGI
acts upstream of negative effect reelin-mediated signaling pathway IMP
IMP: 通过突变表型推断
17974915 MGI
involved in regulation of neuron migration IMP
IMP: 通过突变表型推断
17974915 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Cul5-RING ubiquitin ligase complex IMP
IMP: 通过突变表型推断
17974915 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cullin-5

CUL-5

vasopressin-activated calcium-mobilizing receptor protein

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03364 CUL5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20711 Cul5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27222 Cul5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cul5 NCBI NCBI:8065
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z