2. Gene
  3. Senp2 - SUMO/sentrin specific peptidase 2 Gene

Senp2 - SUMO/sentrin specific peptidase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: SuPr-1; Smt3ip2; mKIAA1331; 2310007L05Rik; 4930538C18Rik

基因 ID: 75826 | 基因类型: protein coding

关于 Senp2

功能概要

Enables SUMO-specific isopeptidase activity. Involved in fat cell differentiation and protein desumoylation. Acts upstream of or within several processes, including embryonic placenta development; negative regulation of DNA damage response, signal transduction by p53 class mediator; and regulation of cell cycle process. Located in cytoplasmic vesicle and nuclear body. Colocalizes with PML body. Is expressed in several structures, including blastocyst; central nervous system; early embryo; extraembryonic component; and retina. Orthologous to human SENP2 (SUMO specific peptidase 2). [provided by Alliance of Genome Resources, Apr 2022]

Senp2 基因产物(2)

mRNA Protein Name
NM_001357424.1 NP_001344353.1 sentrin-specific protease 2 isoform 2
NM_029457.3 NP_083733.1 sentrin-specific protease 2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables deSUMOylase activity IDA
IDA: 通过直接分析推断
12419228 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in fat cell differentiation IDA
IDA: 通过直接分析推断
20194620 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
20417598 MGI
acts upstream of or within labyrinthine layer development IMP
IMP: 通过突变表型推断
19090619 MGI
acts upstream of or within negative regulation of chromatin binding IMP
IMP: 通过突变表型推断
20417598 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
20417598 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
20417598 MGI
acts upstream of or within protein desumoylation IDA
IDA: 通过直接分析推断
15767674 MGI
involved in protein desumoylation IDA
IDA: 通过直接分析推断
12419228 MGI
acts upstream of or within protein desumoylation IMP
IMP: 通过突变表型推断
20417598 MGI
acts upstream of or within regulation of DNA endoreduplication IMP
IMP: 通过突变表型推断
19090619 MGI
acts upstream of or within regulation of G1/S transition of mitotic cell cycle IMP
IMP: 通过突变表型推断
19090619 MGI
acts upstream of or within spongiotrophoblast layer development IMP
IMP: 通过突变表型推断
19090619 MGI
acts upstream of or within trophoblast giant cell differentiation IMP
IMP: 通过突变表型推断
19090619 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
colocalizes with PML body IDA
IDA: 通过直接分析推断
12419228 MGI
located in nuclear body IDA
IDA: 通过直接分析推断
20417598 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sentrin-specific protease 2

SUMO-1 protease-1

SUMO-1/Smt3-specific isopeptidase 2

SUMO/sentrin specific protease 2

axam2

sentrin/SUMO-specific protease SENP2

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100708 NSC632839 Inhibitor 98.87% 否
HY-151358 SENP2-IN-1 Inhibitor 98.05% 否
HY-RS14025 SUMO1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS12672 SENP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18079 Senp2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24554 Senp2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Senp2 NCBI NCBI:59343
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