1. Gene
  2. Slc38a3 - solute carrier family 38, member 3 Gene

Slc38a3 - solute carrier family 38, member 3 Gene

种属: Mus musculus

同用名: Sn1; Nat1; mNAT; Snat3; D9Ucla2; Slc38-3; 0610012J02Rik

基因 ID: 76257 | 基因类型: protein coding

关于 Slc38a3

功能概要

Enables L-glutamine transmembrane transporter activity and L-histidine transmembrane transporter activity. Acts upstream of or within amino acid transport; cellular response to potassium ion starvation; and positive regulation of transcription from RNA polymerase II promoter in response to acidic pH. Located in apical plasma membrane. Is integral component of plasma membrane. Is expressed in several structures, including central nervous system; metanephros; pancreas; pericardium; and retina. Orthologous to human SLC38A3 (solute carrier family 38 member 3). [provided by Alliance of Genome Resources, Apr 2022]

Slc38a3 基因产物(3)

mRNA Protein Name
NM_001199217.1 NP_001186146.1 sodium-coupled neutral amino acid transporter 3
NM_001199218.1 NP_001186147.1 sodium-coupled neutral amino acid transporter 3
NM_023805.3 NP_076294.2 sodium-coupled neutral amino acid transporter 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables L-asparagine, sodium:proton antiporter activity IDA
IDA: 通过直接分析推断
16249471 MGI
enables L-glutamine transmembrane transporter activity IDA
IDA: 通过直接分析推断
10716701 MGI
enables L-glutamine, sodium:proton antiporter activity IDA
IDA: 通过直接分析推断
16249471 MGI
enables L-histidine transmembrane transporter activity IDA
IDA: 通过直接分析推断
10716701 MGI
enables L-histidine, sodium:proton antiporter activity IDA
IDA: 通过直接分析推断
15899884 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in L-glutamine import across plasma membrane IDA
IDA: 通过直接分析推断
18689705 MGI
involved in L-histidine import across plasma membrane IDA
IDA: 通过直接分析推断
15899884 MGI
acts upstream of or within cellular response to potassium ion starvation IDA
IDA: 通过直接分析推断
19458124 MGI
involved in glutamine secretion IDA
IDA: 通过直接分析推断
29561757 MGI
acts upstream of or within glutamine transport IDA
IDA: 通过直接分析推断
10716701 MGI
acts upstream of or within histidine transport IDA
IDA: 通过直接分析推断
10716701 MGI
involved in intracellular amino acid homeostasis IMP
IMP: 通过突变表型推断
26490457 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
19458124 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
32046769 MGI
located in membrane IDA
IDA: 通过直接分析推断
19458124 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
10716701 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

sodium-coupled neutral amino acid transporter 3

N system amino acids transporter NAT-1

N-system amino acid transporter 1

Na(+)-coupled neutral amino acid transporter 3

system N amino acid transporter 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc38a3 NCBI NCBI:10991