1. Gene
  2. Apex2 - apurinic/apyrimidinic endonuclease 2 Gene

Apex2 - apurinic/apyrimidinic endonuclease 2 Gene

种属: Mus musculus

同用名: ape2; C430040P13Rik

基因 ID: 77622 | 基因类型: protein coding

关于 Apex2

功能概要

Predicted to enable DNA-(apurinic or apyrimidinic site) Endonuclease activity; double-stranded DNA 3'-5' exodeoxyribonuclease activity; and phosphoric diester hydrolase activity. Predicted to be involved in base-excision repair. Predicted to act upstream of or within DNA recombination and DNA repair. Located in mitochondrial inner membrane and nucleus. Orthologous to human APEX2 (apurinic/apyrimidinic endodeoxyribonuclease 2). [provided by Alliance of Genome Resources, Apr 2022]

Apex2 基因产物(1)

mRNA Protein Name
NM_029943.3 NP_084219.1 DNA-(apurinic or apyrimidinic site) endonuclease 2
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
12573260 MGI
located in nucleus IDA
IDA: 通过直接分析推断
12573260 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

DNA-(apurinic or apyrimidinic site) endonuclease 2

AP endonuclease 2

APEX nuclease 2

DNA-(apurinic or apyrimidinic site) lyase 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Apex2 NCBI NCBI:27301