Nuak1 - NUAK family, SNF1-like kinase, 1 Gene

中文名称：NUAK 家族，SNF1 样激酶，1

种属: Mus musculus

同用名: Omphk1; B230104P22Rik

关于 Nuak1

功能概要

预计该基因编码的蛋白可启动 p53 结合活性和蛋白丝氨酸/苏氨酸激酶活性。预计参与多个过程，包括细胞对葡萄糖饥饿的反应；细胞衰老的调节；和肌球蛋白轻链磷酸酶活性的调节。预测作用于细胞粘附的上游或内部；细胞对 DNA 损伤刺激的反应；和磷酸化。预计位于纤维中心；微管细胞骨架；和核质。预计在细胞质中有活性。以多种结构表达，包括消化系统；胚胎外胚层；神经系统;鼻子;和泌尿系统。与人类 NUAK1（NUAK 家族激酶 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable p53 binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular response to glucose starvation; regulation of cellular senescence; and regulation of myosin-light-chain-phosphatase activity. Predicted to act upstream of or within cell adhesion; cellular response to DNA damage stimulus; and phosphorylation. Predicted to be located in fibrillar center; microtubule cytoskeleton; and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; embryo ectoderm; nervous system; nose; and urinary system. Orthologous to human NUAK1 (NUAK family kinase 1). [provided by Alliance of Genome Resources, Apr 2022]