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  2. Epha5 - EPH receptor A5 Gene

Epha5 - EPH receptor A5 Gene

种属: Rattus norvegicus

同用名: Els1; EHK-1; Els1.

基因 ID: 79208 | 基因类型: protein coding

关于 Epha5

功能概要

Enables Ephrin Receptor activity and growth factor binding activity. Involved in several processes, including cAMP-mediated signaling; dendritic spine morphogenesis; and Ephrin Receptor signaling pathway. Acts upstream of or within negative regulation of cell adhesion. Located in axon and plasma membrane. Orthologous to human EphA5 (EPH receptor A5). [provided by Alliance of Genome Resources, Apr 2022]

Epha5 基因产物(2)

mRNA Protein Name
NM_001169137.3 NP_001162608.1 ephrin type-A receptor 5 isoform 1 precursor
NM_024367.2 NP_077343.1 ephrin type-A receptor 5 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ephrin receptor activity IDA
IDA: 通过直接分析推断
20824214 RGD
enables growth factor binding IPI
IPI: 通过物理相互作用推断
22568954 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
20824214 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cAMP-mediated signaling IDA
IDA: 通过直接分析推断
20824214 RGD
involved in dendritic spine morphogenesis IDA
IDA: 通过直接分析推断
20824214 RGD
involved in ephrin receptor signaling pathway IDA
IDA: 通过直接分析推断
20824214 RGD
acts upstream of or within negative regulation of cell adhesion IDA
IDA: 通过直接分析推断
23242526 RGD
involved in positive regulation of CREB transcription factor activity IMP
IMP: 通过突变表型推断
20824214 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
7748564 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
7748564 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ephrin type-A receptor 5

EPH homology kinase 1

eck-like sequence 1

tyrosine-protein kinase receptor EHK-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Epha5 NCBI NCBI:2044
Macaca fascicularis Epha5 NCBI NCBI:102138762
Mus musculus Epha5 NCBI NCBI:13839