1. Gene
  2. Chrna1 - cholinergic receptor nicotinic alpha 1 subunit Gene

Chrna1 - cholinergic receptor nicotinic alpha 1 subunit Gene

种属: Rattus norvegicus

基因 ID: 79557 | 基因类型: protein coding

关于 Chrna1

功能概要

Enables acetylcholine-gated cation-selective channel activity. Involved in cation transport and skeletal muscle contraction. Part of acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 1A and congenital myasthenic syndrome 1B. Orthologous to human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrna1 基因产物(1)

mRNA Protein Name
NM_024485.2 NP_077811.1 acetylcholine receptor subunit alpha precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables acetylcholine-gated monoatomic cation-selective channel activity IDA
IDA: 通过直接分析推断
1702709 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in monoatomic cation transport IDA
IDA: 通过直接分析推断
22461452 RGD
involved in skeletal muscle contraction IDA
IDA: 通过直接分析推断
22461452 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of acetylcholine-gated channel complex IDA
IDA: 通过直接分析推断
22461452 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

acetylcholine receptor subunit alpha

cholinergic receptor nicotinic alpha polypeptide 1

cholinergic receptor, nicotinic, alpha 1 (muscle)

cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chrna1 NCBI NCBI:1134
Mus musculus Chrna1 NCBI NCBI:11435