1. Gene
  2. PGBD5 - piggyBac transposable element derived 5 Gene

PGBD5 - piggyBac transposable element derived 5 Gene

中文名称:piggyBac 转座子衍生 5

种属: Homo sapiens

基因 ID: 79605 | 基因类型: protein coding

关于 PGBD5

Cytogenetic location: 1q42.13 Genomic coordinates (GRCh38): 1:230,314,490-230,426,332 (from NCBI)

This gene has 3 transcripts (splice variants) and 202 orthologues. Biased expression in brain (RPKM 13.1), adrenal (RPKM 4.4) and 9 other tissues.

功能概要

在多种动物中发现的 piggyBac 蛋白质家族是与来自蛾 Trichoplusia ni 的典型 piggyBac 转座子的转座酶相关的转座酶。该家族还包括几个基因组中的基因,包括人类基因组,这些基因似乎源自 piggyBac 转座子。该基因属于 piggyBac 转座因子衍生 (PGBD) 基因亚科。 PGBD 蛋白质似乎是新的,与其他转座酶或其他已知蛋白质家族没有明显关系。[RefSeq 提供,2010 年 5 月]

The piggyBac family of proteins, found in diverse Animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to Other transposases, or Other known protein families. [provided by RefSeq, May 2010]

PGBD5 基因产物(1)

mRNA Protein Name
NM_001258311.2 NP_001245240.1 piggyBac transposable element-derived protein 5
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables transposase activity IDA
IDA: 通过直接分析推断
26406119 GOA
enables transposase activity IMP
IMP: 通过突变表型推断
27491780 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in non-replicative DNA transposition IMP
IMP: 通过突变表型推断
26406119 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PGBD5 蛋白结构

DDE_Tnp_1_7

DDE_Tnp_1_7: Transposase IS4 (52 - 418)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 455 a.a.
蛋白主名 其他名称

piggyBac transposable element-derived protein 5

piggyBac domain related protein 5

关联疾病

疾病名称 别名
Glioblastoma Proneural Subtype
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PGBD5 VGNC VGNC:100033
Bos taurus PGBD5 VGNC VGNC:32784
Mus musculus PGBD5 MGD MGI:2429955
Rattus norvegicus PGBD5 RGD RGD:1310825
Canis familiaris PGBD5 VGNC VGNC:44455
Felis catus PGBD5 VGNC VGNC:64121