2. Gene
  3. VEPH1 - ventricular zone expressed PH domain containing 1 Gene

VEPH1 - ventricular zone expressed PH domain containing 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：含心室区表达的 PH 结构域 1

种属: Homo sapiens

同用名: MELT; VEPH

基因 ID: 79674 | 基因类型: protein coding

关于 VEPH1

Cytogenetic location: 3q25.31-q25.32 Genomic coordinates (GRCh38): 3:157,259,742-157,503,605 (from NCBI)

This gene has 19 transcripts (splice variants) and 200 orthologues. Biased expression in lung (RPKM 12.0), adrenal (RPKM 8.2) and 8 other tissues.

功能概要

预测可启用磷脂酰肌醇-5-磷酸结合活性。参与 SMAD 蛋白信号转导的负调控和转化生长因子β受体信号通路的负调控。预计在质膜上有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable phosphatidylinositol-5-phosphate binding activity. Involved in negative regulation of SMAD protein signal transduction and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

VEPH1 基因产物(6)

mRNA Protein Name
NM_001167911.2 NP_001161383.1 ventricular zone-expressed PH domain-containing protein homolog 1 isoform 2
NM_001167912.2 NP_001161384.1 ventricular zone-expressed PH domain-containing protein homolog 1 isoform 1
NM_001167915.3 NP_001161387.1 ventricular zone-expressed PH domain-containing protein homolog 1 isoform 3
NM_001167916.3 NP_001161388.1 ventricular zone-expressed PH domain-containing protein homolog 1 isoform 3
NM_001167917.1 NP_001161389.1 ventricular zone-expressed PH domain-containing protein homolog 1 isoform 5
NM_024621.2 NP_078897.2 ventricular zone-expressed PH domain-containing protein homolog 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
30126976 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of SMAD protein signal transduction IDA
IDA: 通过直接分析推断
26039994 GOA
involved in negative regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: 通过直接分析推断
26039994 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

VEPH1 蛋白结构

PH

PH: PH domain (719 - 816)

  • 0
  • 200
  • 400
  • 600
  • 833 a.a.
蛋白主名 其他名称

ventricular zone-expressed PH domain-containing protein homolog 1

protein melted

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15640 VEPH1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21804 Veph1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28320 Veph1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus VEPH1 VGNC VGNC:66939
Canis familiaris VEPH1 VGNC VGNC:48255
Mus musculus VEPH1 MGD MGI:1920039
Bos taurus VEPH1 VGNC VGNC:36787
Macaca mulatta VEPH1 VGNC VGNC:79535
Rattus norvegicus VEPH1 RGD RGD:1308217
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