2. Gene
  3. ZNF750 - zinc finger protein 750 Gene

ZNF750 - zinc finger protein 750 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：锌指蛋白 750

种属: Homo sapiens

同用名: SLDPE; ZFP750

基因 ID: 79755 | 基因类型: protein coding

关于 ZNF750

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:82,829,434-82,840,022 (from NCBI)

This gene has 2 transcripts (splice variants), 202 orthologues, 2 paralogues and is associated with 3 phenotypes. Biased expression in esophagus (RPKM 37.2), skin (RPKM 25.3) and 5 other tissues.

功能概要

该基因编码一种具有核定位位点和 C2H2 锌指结构域的蛋白质。该基因的突变与具有牛皮癣样成分的脂溢性皮炎有关。[RefSeq 提供，2008 年 7 月]

This gene encodes a protein with a nuclear localization site and a C2H2 zinc finger domain. Mutations in this gene have been associated with seborrhea-like dermatitis with psoriasiform elements. [provided by RefSeq, Jul 2008]

ZNF750 基因产物(1)

mRNA Protein Name
NM_024702.3 NP_078978.2 zinc finger protein 750
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
22364861 GOA
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
32042337 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
22364861 GOA
enables promoter-specific chromatin binding IDA
IDA: 通过直接分析推断
27907090 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in epidermis development IMP
IMP: 通过突变表型推断
22364861 GOA
involved in negative regulation of epithelial to mesenchymal transition IMP
IMP: 通过突变表型推断
32042337 GOA
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
32042337 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
22364861 GOA
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
27907090 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
22364861 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZNF750 蛋白结构

zf-C2H2_7

zf-C2H2_7: Zinc-finger (5 - 58)

  • 0
  • 200
  • 400
  • 600
  • 723 a.a.
蛋白主名 其他名称

zinc finger protein 750

protein ZNF750

关联疾病

疾病名称 别名
Seborrhea-Like Dermatitis With Psoriasiform Elements

SLDP
Dermatitis

Eczema

Skin Inflammation

Inflammatory Dermatosis
Seborrheic Dermatitis

Seborrhoeic Dermatitis

Seborrhea

Seborrhoeic Eczema

Skin Seborrheic

Dermatitis, Seborrheic
Rectosigmoid Junction Neoplasm

Neoplasm Of Rectosigmoid Junction

Rectosigmoid Neoplasm

Rectosigmoid Tumor

Rectosigmoid Carcinoma

Carcinoma Of The Rectosigmoid Junction

Malignant Tumor Of Rectosigmoid Junction

Rectosigmoid Junction Cancer

Primary Malignant Neoplasm Of Rectosigmoid Junction

Rectosigmoid Colon Cancer

Carcinoma Of Rectum With Sigmoid

Colorectal Cancer Nos

Colorectal Carcinoma Nos

Rectosigmoid Cancer
Squamous Cell Carcinoma

Epidermoid Carcinoma

Squamous Cell Cancer

Carcinoma, Squamous Cell

Squamous Cell Skin Cancer

Malignant Squamous Cell Tumor

Squamous Carcinoma

Squamous Cell Epithelioma

Carcinoma Squamous Cell

Neoplasms, Squamous Cell

Squamous Cell Carcinoma - Category

Malignant Squamous Cell Neoplasm

Squamous Cell Carcinoma Of Skin
Sigmoid Neoplasm

Sigmoid Neoplasms

Neoplasm Of Sigmoid Colon

Tumor Of Sigmoid Colon
Lung Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Lung

Squamous Cell Lung Carcinoma

Epidermoid Cell Carcinoma Of The Lung

Squamous Cell Lung Cancer
Eyelid Carcinoma

Carcinoma Of The Eyelid
Seborrheic Infantile Dermatitis

Cradle Cap

Infantile Seborrhoeic Dermatitis

Seborrhoea Capitis

Seborrhoeic Dermatitis Of Scalp

Seborrhoeic Eczema Of Scalp

Complement 5 Dysfunction

Generalized Seborrheic Dermatitis Of Infants

Infantile Seborrheic Dermatitis

Pityriasis Capitis

Seborrhea Capitis

Seborrhea Sicca

Dandruff

Complement Component 5 Deficiency

Seborrheic Dermatitis

Seborrheic Dermatitis Of Scalp

Scurfiness Of Scalp

Seborrheic Dermatitis Of Infancy

Infantile Seborrhoeic Eczema

Neonatal Seborrhoeic Dermatitis

Infantile Seborrhoeic Dermatitis Of The Scalp
Muir-Torre Syndrome

MRTES

Keratoacanthoma

Muir-Torré Syndrome

Cutaneous Sebaceous Neoplasms And Keratoacanthomas, Multiple, With Gastrointestinal And Other Carcinomas

Cutaneous Sebaceous Neoplasms And Keratoacanthomas Multiple With Gastrointestinal And Other Carcinomas

Multiple Keratoacanthoma, Muir-Torre Type

Mts

Torre-Muir Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16173 ZNF750 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ZNF750 RGD RGD:1590044
Mus musculus ZNF750 MGD MGI:2442210
Felis catus ZNF750 VGNC VGNC:67354
Canis familiaris ZNF750 VGNC VGNC:48810
Bos taurus ZNF750 VGNC VGNC:37340
Macaca mulatta ZNF750 VGNC VGNC:104679
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