2. Gene
  3. ADM2 - adrenomedullin 2 Gene

ADM2 - adrenomedullin 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：肾上腺髓质素 2

种属: Homo sapiens

同用名: AM2; dJ579N16.4

基因 ID: 79924 | 基因类型: protein coding

关于 ADM2

Cytogenetic location: 22q13.33 Genomic coordinates (GRCh38): 22:50,481,543-50,486,437 (from NCBI)

This gene has 2 transcripts (splice variants), 222 orthologues and 1 paralogue. Biased expression in thyroid (RPKM 8.0), kidney (RPKM 5.1) and 12 other tissues.

功能概要

该基因编码降钙素基因相关肽 (CGRP) /降钙素激素家族的成员，这些激素在调节心血管稳态、催乳素释放、抗利尿、抗尿钠排泄以及调节食物和水的摄入方面发挥作用。编码的蛋白质经过蛋白水解处理以产生一种或多种生物活性肽。[RefSeq 提供，2015 年 7 月]

This gene encodes a member of the Calcitonin gene-related peptide (CGRP)/Calcitonin family of Hormones that play a role in the regulation of cardiovascular homeostasis, Prolactin release, anti-diuresis, anti-natriuresis, and regulation of food and water intake. The encoded protein is proteolytically processed to generate one or more biologically active peptides. [provided by RefSeq, Jul 2015]

ADM2 基因产物(2)

mRNA Protein Name
NM_001253845.2 NP_001240774.1 protein ADM2 preproprotein
NM_001369882.1 NP_001356811.1 protein ADM2 preproprotein

ADM2 蛋白结构

Calc_CGRP_IAPP

Calc_CGRP_IAPP: Calcitonin / CGRP / IAPP family (104 - 148)

  • 0
  • 100
  • 148 a.a.
蛋白主名 其他名称

protein ADM2

intermedin

关联疾病

疾病名称 别名
Immunodeficiency 53

IMD53
Coronary Stenosis

Coronary Artery Stenosis
Charcot-Marie-Tooth Disease, X-Linked Recessive, 3

CMTX3

Charcot-Marie-Tooth Disease X-Linked Recessive 3

Charcot-Marie-Tooth Neuropathy, X-Linked Recessive, 3

Cmt3x

X-Linked Charcot-Marie-Tooth Disease Type 3

Charcot-Marie-Tooth Neuropathy X-Linked Recessive 3

Charcot-Marie-Tooth Disease, X-Linked Type 3, Recessive
Myopathy, Centronuclear, 2

Myopathy, Centronuclear, Autosomal Recessive

Autosomal Recessive Centronuclear Myopathy

CNM2

Centronuclear Myopathy 2

Ar-Cnm

Myotubular Myopathy, Autosomal Recessive

Autosomal Recessive Myotubular Myopathy

Centronuclear Myopathy Autosomal Recessive

Myopathy, Centronuclear, Type 2
Epiphyseal Dysplasia, Multiple, 1

EDM1

Multiple Epiphyseal Dysplasia 1

Multiple Epiphyseal Dysplasia Type 1

Med1

Multiple Epiphyseal Dysplasia Comp-Related

Polyepiphyseal Dysplasia Type 1

Multiple Epiphyseal Dysplasia, Comp-Related

Epiphyseal Dysplasia Multiple 1

Epiphyseal Dysplasia, Multiple 1

Dysplasia, Epiphyseal, Multiple, Type 1
Multiple Epiphyseal Dysplasia Due To Collagen 9 Anomaly
Migraine With Or Without Aura 1

Migraine

Migraine With Or Without Aura, Susceptibility To, 1

Migraine Disorder

Migraine Variant

Migraines

Migraine Disorders

Mgr1

Mgau

Ma

Migraine With Or Without Aura

Classic Migraine

Common Migraine

Disorder, Migraine

Headache Migraine

Headache Migrainous

Migraine Headache

Migraine Syndrome

Headache Including Migraine

Migraine, Susceptibility To
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N0876 Arenobufagin Inducer 99.86% 否
HY-N1514 Ganoderenic acid B 99.95% 否
HY-RS00387 ADM2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20246 Adm2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26754 Adm2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ADM2 VGNC VGNC:37661
Felis catus ADM2 VGNC VGNC:83486
Macaca mulatta ADM2 VGNC VGNC:107731
Mus musculus ADM2 MGD MGI:2675256
Bos taurus ADM2 VGNC VGNC:25682
Rattus norvegicus ADM2 RGD RGD:1302971
Others ADM2 NCBI
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