1. Gene
  2. Lrba - LPS-responsive beige-like anchor Gene

Lrba - LPS-responsive beige-like anchor Gene

种属: Mus musculus

同用名: Lba; Lab300; D3Ertd775e

基因 ID: 80877 | 基因类型: protein coding

关于 Lrba

功能概要

Predicted to enable protein kinase A binding activity and protein kinase binding activity. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Located in several cellular components, including endoplasmic reticulum; lysosome; and trans-Golgi network. Is expressed in branchial arch; central nervous system; limb; sensory organ; and somite. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human LRBA (LPS responsive beige-like anchor protein). [provided by Alliance of Genome Resources, Apr 2022]

Lrba 基因产物(3)

mRNA Protein Name
NM_001077687.1 NP_001071155.1 lipopolysaccharide-responsive and beige-like anchor protein isoform gamma
NM_001077688.1 NP_001071156.1 lipopolysaccharide-responsive and beige-like anchor protein isoform beta
NM_030695.2 NP_109620.2 lipopolysaccharide-responsive and beige-like anchor protein isoform alpha
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
11254716 MGI
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
11254716 MGI
located in lysosome IDA
IDA: 通过直接分析推断
11254716 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
11254716 MGI
located in trans-Golgi network IDA
IDA: 通过直接分析推断
11254716 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

lipopolysaccharide-responsive and beige-like anchor protein

beige-like protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lrba NCBI NCBI:987