2. Gene
  3. Tbl1xr1 - transducin (beta)-like 1X-linked receptor 1 Gene

Tbl1xr1 - transducin (beta)-like 1X-linked receptor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: C21; DC42; Ira1; TBLR1; 8030499H02Rik; A630076E03Rik; C230089I12Rik

基因 ID: 81004 | 基因类型: protein coding

关于 Tbl1xr1

功能概要

Enables transcription cis-regulatory region binding activity and transcription corepressor activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including blastocyst hatching; fat pad development; and white fat cell differentiation. Predicted to be located in mitotic spindle and nucleus. Predicted to be part of histone deacetylase complex and transcription repressor complex. Is expressed in early conceptus; secondary oocyte; and thymus primordium. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 41. Orthologous to human TBL1XR1 (TBL1X receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Tbl1xr1 基因产物(1)

mRNA Protein Name
NM_030732.3 NP_109657.2 F-box-like/WD repeat-containing protein TBL1XR1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
14980219 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
14980219 MGI
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
16127449 MGI
enables transcription corepressor activity IMP
IMP: 通过突变表型推断
14980219 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adipose tissue development IMP
IMP: 通过突变表型推断
23499424 MGI
acts upstream of or within blastocyst hatching IMP
IMP: 通过突变表型推断
27869233 MGI
acts upstream of or within fat pad development IMP
IMP: 通过突变表型推断
23499424 MGI
acts upstream of or within lipid catabolic process IMP
IMP: 通过突变表型推断
23499424 MGI
acts upstream of or within multicellular organism growth IMP
IMP: 通过突变表型推断
23499424 MGI
acts upstream of or within negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
14980219 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
16127449 MGI
acts upstream of or within proteasome-mediated ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
14980219 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
23499424 MGI
acts upstream of or within regulation of triglyceride metabolic process IMP
IMP: 通过突变表型推断
23499424 MGI
acts upstream of or within response to dietary excess IMP
IMP: 通过突变表型推断
23499424 MGI
acts upstream of or within white fat cell differentiation IMP
IMP: 通过突变表型推断
23499424 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

F-box-like/WD repeat-containing protein TBL1XR1

F-box-like/WD repeat protein TBL1XR1

TBL1-related protein 1

nuclear receptor corepressor/HDAC3 complex subunit TBLR1

transducin beta-like 1X-related protein 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14262 TBL1XR1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20223 Tbl1xr1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26730 Tbl1xr1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tbl1xr1 NCBI NCBI:79718
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