2. Gene
  3. DPF3 - double PHD fingers 3 Gene

DPF3 - double PHD fingers 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：双 PHD 手指 3

种属: Homo sapiens

同用名: CERD4; BAF45C; SMARCG3

基因 ID: 8110 | 基因类型: protein coding

关于 DPF3

Cytogenetic location: 14q24.2 Genomic coordinates (GRCh38): 14:72,609,034-72,894,101 (from NCBI)

This gene has 14 transcripts (splice variants), 208 orthologues and 9 paralogues. Biased expression in ovary (RPKM 2.9), heart (RPKM 2.2) and 11 other tissues.

功能概要

该基因编码 D4 蛋白家族的一个成员。编码的蛋白质是结合乙酰化组蛋白的转录调节因子，是 BAF 染色质重塑复合物的组成部分。交替剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2013 年 7 月]

This gene encodes a member of the D4 protein family. The encoded protein is a transcription regulator that binds acetylated histones and is a component of the BAF chromatin remodeling complex. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

DPF3 基因产物(4)

mRNA Protein Name
NM_001280542.3 NP_001267471.1 zinc finger protein DPF3 isoform 2
NM_001280543.2 NP_001267472.1 zinc finger protein DPF3 isoform 3
NM_001280544.2 NP_001267473.1 zinc finger protein DPF3 isoform 4
NM_012074.5 NP_036206.3 zinc finger protein DPF3 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32459350 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

DPF3 蛋白结构

Requiem_N

Requiem_N: N-terminal domain of DPF2/REQ. (13 - 84)

PHD

PHD: PHD-finger (319 - 363)

  • 0
  • 100
  • 200
  • 300
  • 378 a.a.
蛋白主名 其他名称

zinc finger protein DPF3

BRG1-associated factor 45C

关联疾病

疾病名称 别名
Melanomatosis
Atrial Septal Defect 9

ASD9

Atrial Heart Septal Defect 9

Septal Defect, Atrial, Type 9
Tetralogy Of Fallot

TOF

Fallot Tetralogy

Ventricular Septal Defect With Pulmonary Stenosis Or Atresia, Dextraposition Of Aorta, And Hypertrophy Of Right Ventricle

Tetrad Of Fallot

Fallot Tetrad

Fallot Disease

Fallot Complex

Subpulmonic Stenosis, Ventricular Septal Defect, Overriding Aorta, And Right Ventricular Hypertrophy

Interventricular Septal Defect With Dextroposition Of Aorta, Pulmonary Stenosis And Hypertrophy Of Right Ventricle

Interventricular Septal Defect, In Tetralogy Of Fallot

Ventricular Septal Defect With Obstructed Right Ventricular Outflow

Tof - [Tetralogy Of Fallot]

Pulmonary Atresia With Ventricular Septal Defect [Fallot Type]

Pulmonary Atresia, Ventricular Septal Defect And Mapcas

Pulmonary Atresia With Ventricular Septal Defect And Systemic-To-Pulmonary Collateral Arteries [Fallot Type]
Hirschsprung Disease 1

Hirschsprung Disease

Aganglionic Megacolon

Hscr

Hirschsprung'S Disease

Congenital Megacolon

Congenital Intestinal Aganglionosis

Colonic Aganglionosis

Hirschsprung Disease, Susceptibility To, 1

Hirschsprung Disease, Protection Against

HSCR1

Mgc

Pelvirectal Achalasia

Total Intestinal Aganglionosis

Megacolon, Aganglionic

Macrocolon

Hscr 1

Hirschsprung Disease Type 1

Hirschsprung Disease, Type 1

Congenital Dilatation Of Colon

Aganglionosis

Congenital Aganglionic Megacolon

Aganglionosis Of Colon

Bowel Aganglionosis

Colon Aganglionosis

Hirschsprung Megacolon
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03951 DPF3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta DPF3 VGNC VGNC:99198
Bos taurus DPF3 VGNC VGNC:28177
Felis catus DPF3 VGNC VGNC:61595
Mus musculus DPF3 MGD MGI:1917377
Rattus norvegicus DPF3 RGD RGD:1309052
Canis familiaris DPF3 VGNC VGNC:50524
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