2. Gene
  3. Acta2 - actin alpha 2, smooth muscle Gene

Acta2 - actin alpha 2, smooth muscle Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 81633 | 基因类型: protein coding

关于 Acta2

功能概要

Predicted to enable protein kinase binding activity. Involved in several processes, including positive regulation of ERK1 and ERK2 cascade; positive regulation of cellular component movement; and positive regulation of hepatic stellate cell activation. Located in cytoplasm and stress fiber. Human ortholog(s) of this gene implicated in Moyamoya disease and thoracic aortic aneurysm. Orthologous to human ACTA2 (actin alpha 2, smooth muscle). [provided by Alliance of Genome Resources, Apr 2022]

Acta2 基因产物(1)

mRNA Protein Name
NM_031004.2 NP_112266.1 actin, aortic smooth muscle
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to transforming growth factor beta stimulus IEP
IEP: 通过表达模式推断
17043753 RGD
involved in juxtaglomerular apparatus development IEP
IEP: 通过表达模式推断
30645697 RGD
involved in muscle contraction IDA
IDA: 通过直接分析推断
11953441 RGD
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
24204762 RGD
involved in positive regulation of hepatic stellate cell activation IMP
IMP: 通过突变表型推断
24204762 RGD
involved in positive regulation of hepatic stellate cell contraction IMP
IMP: 通过突变表型推断
24204762 RGD
involved in positive regulation of hepatic stellate cell migration IMP
IMP: 通过突变表型推断
24204762 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
8616889 RGD
located in basement membrane IDA
IDA: 通过直接分析推断
30476341 RGD
located in stress fiber IDA
IDA: 通过直接分析推断
24204762 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

actin, aortic smooth muscle

actin, alpha 2, smooth muscle, aorta

alpha-actin-2

smooth muscle alpha-actin

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00214 ACTA2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-175496 Acid Ceramidase-IN-3 Inhibitor / 否
HY-RS19169 Acta2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22375 Acta1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25658 Acta2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Acta2 NCBI NCBI:59
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z