2. Gene
  3. Msh2 - mutS homolog 2 Gene

Msh2 - mutS homolog 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 81709 | 基因类型: protein coding

关于 Msh2

功能概要

Predicted to enable several functions, including ATP hydrolysis activity; DNA binding activity; and protein C-terminus binding activity. Predicted to contribute to several functions, including DNA binding activity; MutLalpha complex binding activity; and adenyl ribonucleotide binding activity. Involved in several processes, including response to amino acid; response to xenobiotic stimulus; and spermatogenesis. Located in nucleus. Biomarker of colitis and visual epilepsy. Human ortholog(s) of this gene implicated in several diseases, including Lynch syndrome (multiple); gastrointestinal system Cancer (multiple); lung Cancer (multiple); mismatch repair Cancer syndrome; and transitional cell carcinoma. Orthologous to human MSH2 (mutS homolog 2). [provided by Alliance of Genome Resources, Apr 2022]

Msh2 基因产物(1)

mRNA Protein Name
NM_031058.2 NP_112320.2 DNA mismatch repair protein Msh2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to amino acid IEP
IEP: 通过表达模式推断
11026496 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
18095365 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
11056294 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
9034308 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA mismatch repair protein Msh2

mismatch repair protein

mutS protein homolog 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08709 MSH2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18622 Msh2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25108 Msh2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Msh2 NCBI NCBI:4436
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