2. Gene
  3. Actr3 - actin related protein 3 Gene

Actr3 - actin related protein 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Arp3

基因 ID: 81732 | 基因类型: protein coding

关于 Actr3

功能概要

Enables ATPase binding activity and actin binding activity. Involved in several processes, including neurogenesis; positive regulation of cellular component organization; and positive regulation of protein localization to membrane. Located in several cellular components, including apical ectoplasmic specialization; basal ectoplasmic specialization; and concave side of sperm head. Part of apical tubulobulbar complex. Is active in glutamatergic synapse and postsynapse. Colocalizes with actin filament. Used to study focal segmental glomerulosclerosis. Biomarker of focal segmental glomerulosclerosis and schizophrenia. Human ortholog(s) of this gene implicated in opisthorchiasis. Orthologous to human ACTR3 (actin related protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Actr3 基因产物(1)

mRNA Protein Name
NM_031068.1 NP_112330.1 actin-related protein 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATPase binding IPI
IPI: 通过物理相互作用推断
23403943 RGD
enables actin binding IDA
IDA: 通过直接分析推断
20566646 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
18064521 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Sertoli cell barrier remodeling IEP
IEP: 通过表达模式推断
20534520 RGD
involved in astrocyte differentiation IMP
IMP: 通过突变表型推断
23843614 RGD
involved in cellular response to epidermal growth factor stimulus IEP
IEP: 通过表达模式推断
10209028 RGD
involved in cellular response to interleukin-1 IEP
IEP: 通过表达模式推断
21191089 RGD
involved in cellular response to pyrimidine ribonucleotide IEP
IEP: 通过表达模式推断
22065602 RGD
involved in cellular response to transforming growth factor beta stimulus IDA
IDA: 通过直接分析推断
22319661 RGD
involved in cellular response to trichostatin A IEP
IEP: 通过表达模式推断
12445420 RGD
involved in cellular response to triterpenoid IEP
IEP: 通过表达模式推断
20566646 RGD
involved in cellular response to tumor necrosis factor IDA
IDA: 通过直接分析推断
22319661 RGD
involved in negative regulation of axon extension IMP
IMP: 通过突变表型推断
19846719 RGD
involved in negative regulation of bleb assembly IMP
IMP: 通过突变表型推断
22786929 RGD
involved in positive regulation of actin filament polymerization IMP
IMP: 通过突变表型推断
18256280 RGD
involved in positive regulation of astrocyte differentiation IMP
IMP: 通过突变表型推断
23843614 RGD
involved in positive regulation of dendrite morphogenesis IMP
IMP: 通过突变表型推断
18430734 RGD
involved in positive regulation of dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
23441206 RGD
involved in positive regulation of fibroblast migration IMP
IMP: 通过突变表型推断
20566646 RGD
involved in positive regulation of filopodium assembly IMP
IMP: 通过突变表型推断
18256280 RGD
involved in positive regulation of lamellipodium assembly IMP
IMP: 通过突变表型推断
18256280 RGD
involved in positive regulation of neuron differentiation IMP
IMP: 通过突变表型推断
18256280 RGD
involved in positive regulation of protein localization to plasma membrane IMP
IMP: 通过突变表型推断
21844200 RGD
involved in positive regulation of protein targeting to membrane IMP
IMP: 通过突变表型推断
20739464 RGD
involved in positive regulation of synapse assembly IMP
IMP: 通过突变表型推断
18430734 RGD
involved in postsynapse organization IDA
IDA: 通过直接分析推断
18430734 RGD
involved in postsynapse organization IMP
IMP: 通过突变表型推断
18430734 RGD
involved in postsynaptic actin cytoskeleton organization IDA
IDA: 通过直接分析推断
18430734 RGD
involved in postsynaptic actin cytoskeleton organization IMP
IMP: 通过突变表型推断
18430734 RGD
involved in regulation of actin cytoskeleton organization IMP
IMP: 通过突变表型推断
20739464 RGD
involved in regulation of myosin II filament organization IMP
IMP: 通过突变表型推断
18256280 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
19095743 RGD
involved in response to heparin IEP
IEP: 通过表达模式推断
17488504 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
20534520 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi membrane IDA
IDA: 通过直接分析推断
15147909 RGD
located in actin filament IDA
IDA: 通过直接分析推断
10209028 RGD
located in apical ectoplasmic specialization IDA
IDA: 通过直接分析推断
23546604 RGD
part of apical tubulobulbar complex IDA
IDA: 通过直接分析推断
22797892 RGD
located in basal ectoplasmic specialization IDA
IDA: 通过直接分析推断
23546604 RGD
located in cell leading edge IDA
IDA: 通过直接分析推断
17855387 RGD
located in cell-cell junction IDA
IDA: 通过直接分析推断
22319661 RGD
located in concave side of sperm head IDA
IDA: 通过直接分析推断
22332112 RGD
located in excitatory synapse IDA
IDA: 通过直接分析推断
18430734 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
18430734 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
18430734 RGD
located in hemidesmosome IDA
IDA: 通过直接分析推断
15093736 RGD
located in lamellipodium IDA
IDA: 通过直接分析推断
15252126 RGD
located in leading edge of lamellipodium IDA
IDA: 通过直接分析推断
17855387 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
22319661 RGD
located in podosome IDA
IDA: 通过直接分析推断
15093736 RGD
located in podosome core IDA
IDA: 通过直接分析推断
24290759 RGD
is active in postsynapse EXP
EXP: 通过实验结果推断
15020595 RGD
is active in postsynapse IDA
IDA: 通过直接分析推断
15020595 RGD
is active in postsynapse IMP
IMP: 通过突变表型推断
18430734 RGD
located in ruffle IDA
IDA: 通过直接分析推断
10209028 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

actin-related protein 3

ARP3 actin related protein 3 homolog

actin-like protein 3

actin-related protein 3 homolog (yest)

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00231 ACTR3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS00232 ACTR3B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19403 Actr3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25895 Actr3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Actr3 NCBI NCBI:10096
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