2. Gene
  3. PDPK1 - Pdpk1 3-phosphoinositide dependent protein kinase-1 Gene

PDPK1 - Pdpk1 3-phosphoinositide dependent protein kinase-1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 81745 | 基因类型: protein coding

关于 PDPK1

功能概要

Enables 3-phosphoinositide-dependent protein kinase activity; Insulin Receptor binding activity; and protein kinase binding activity. Involved in cellular response to brain-derived neurotrophic factor stimulus; focal adhesion assembly; and negative regulation of neuron apoptotic process. Located in cytosol; perikaryon; and plasma membrane. Human ortholog(s) of this gene implicated in prostate Cancer. Orthologous to several human genes including PDPK1 (3-phosphoinositide dependent protein kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

PDPK1 基因产物(1)

mRNA Protein Name
NM_031081.2 NP_112343.2 3-phosphoinositide-dependent protein kinase 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 3-phosphoinositide-dependent protein kinase activity IDA
IDA: 通过直接分析推断
14585963 RGD
enables insulin receptor binding IDA
IDA: 通过直接分析推断
16314505 RGD
enables protein kinase binding IDA
IDA: 通过直接分析推断
14585963 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to brain-derived neurotrophic factor stimulus IEP
IEP: 通过表达模式推断
18971483 RGD
involved in focal adhesion assembly IMP
IMP: 通过突变表型推断
14585963 RGD
involved in negative regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
18971483 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in perikaryon IDA
IDA: 通过直接分析推断
18971483 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

3-phosphoinositide-dependent protein kinase 1

pkB kinase

protein kinase B kinase

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12063 PHT-427 98.09% 否
HY-108263B (R)-3-Hydroxy Midostaurin Inhibitor / 否
HY-RS10287 PDPK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W719359 PHT-427-d4 / 否
HY-RS17027 Pdpk1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23470 Pdpk1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens PDPK1 NCBI NCBI:5170
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z