1. Gene
  2. ELOVL3 - ELOVL fatty acid elongase 3 Gene

ELOVL3 - ELOVL fatty acid elongase 3 Gene

中文名称:ELOVL 脂肪酸延长酶 3

种属: Homo sapiens

同用名: CIG30; CIG-30

基因 ID: 83401 | 基因类型: protein coding

关于 ELOVL3

Cytogenetic location: 10q24.32 Genomic coordinates (GRCh38): 10:102,224,767-102,229,589 (from NCBI)

This gene has 1 transcript (splice variant), 264 orthologues and 6 paralogues. Biased expression in fat (RPKM 1.4), skin (RPKM 0.7) and 8 other tissues.

功能概要

该基因编码属于 GNS1/SUR4 家族的蛋白质。该家族的成员在长链脂肪酸的延伸中发挥作用,为合成鞘脂和神经酰胺提供前体。[RefSeq 提供,2013 年 7 月]

This gene encodes a protein that belongs to the GNS1/SUR4 family. Members of this family play a role in elongation of long chain fatty acids to provide precursors for synthesis of sphingolipids and ceramides. [provided by RefSeq, Jul 2013]

ELOVL3 基因产物(1)

mRNA Protein Name
NM_152310.3 NP_689523.1 elongation of very long chain fatty acids protein 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fatty acid elongase activity EXP
EXP: 通过实验结果推断
10970790 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
20937905 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in fatty acid elongation, monounsaturated fatty acid IDA
IDA: 通过直接分析推断
20937905 GOA
involved in fatty acid elongation, polyunsaturated fatty acid IDA
IDA: 通过直接分析推断
20937905 GOA
involved in fatty acid elongation, saturated fatty acid IDA
IDA: 通过直接分析推断
20937905 GOA
involved in very long-chain fatty acid biosynthetic process IDA
IDA: 通过直接分析推断
20937905 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
20937905 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ELOVL3 蛋白结构

ELO

ELO: GNS1/SUR4 family (32 - 265)

  • 0
  • 100
  • 200
  • 270 a.a.
蛋白主名 其他名称

elongation of very long chain fatty acids protein 3

3-keto acyl-CoA synthase ELOVL3

关联疾病

疾病名称 别名
Spinocerebellar Ataxia 38

Spinocerebellar Ataxia Type 38

SCA38

Ataxia, Spinocerebellar, Type 38

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ELOVL3 VGNC VGNC:72064
Mus musculus ELOVL3 MGD MGI:1195976
Canis familiaris ELOVL3 VGNC VGNC:40321
Rattus norvegicus ELOVL3 RGD RGD:1307263
Bos taurus ELOVL3 VGNC VGNC:28449