2. Gene
  3. ADPGK - ADP dependent glucokinase Gene

ADPGK - ADP dependent glucokinase Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：ADP 依赖性葡萄糖激酶

种属: Homo sapiens

同用名: ADP-GK; 2610017G09Rik

基因 ID: 83440 | 基因类型: protein coding

关于 ADPGK

Cytogenetic location: 15q24.1 Genomic coordinates (GRCh38): 15:72,751,294-72,783,758 (from NCBI)

This gene has 14 transcripts (splice variants) and 202 orthologues. Ubiquitous expression in bone marrow (RPKM 23.6), appendix (RPKM 19.7) and 25 other tissues.

功能概要

ADPGK (EC 2.7.1.147) 催化葡萄糖的 ADP 依赖性磷酸化为葡萄糖-6-磷酸，并可能在糖酵解中发挥作用，可能在缺血条件下 (Ronimus 和 Morgan，2004 [PubMed 14975750]) 。[OMIM 提供， 2008 年 3 月]

ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).[supplied by OMIM, Mar 2008]

ADPGK 基因产物(8)

mRNA Protein Name
NM_001365223.1 NP_001352152.1 ADP-dependent glucokinase isoform 2
NM_001365224.1 NP_001352153.1 ADP-dependent glucokinase isoform 3
NM_001365225.1 NP_001352154.1 ADP-dependent glucokinase isoform 4 precursor
NM_001365226.1 NP_001352155.1 ADP-dependent glucokinase isoform 5
NM_001365227.1 NP_001352156.1 ADP-dependent glucokinase isoform 6 precursor
NM_001365228.1 NP_001352157.1 ADP-dependent glucokinase isoform 7 precursor
NM_001365229.1 NP_001352158.1 ADP-dependent glucokinase isoform 3
NM_031284.5 NP_112574.3 ADP-dependent glucokinase isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ADP-specific glucokinase activity EXP
EXP: 通过实验结果推断
23168256 GOA
enables ADP-specific glucokinase activity IDA
IDA: 通过直接分析推断
26555263 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within glucose metabolic process IDA
IDA: 通过直接分析推断
26555263 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
23168256 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ADPGK 蛋白结构

ADP_PFK_GK

ADP_PFK_GK: ADP-specific Phosphofructokinase/Glucokinase conserved region (69 - 491)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 496 a.a.
蛋白主名 其他名称

ADP-dependent glucokinase

ATP-dependent glucokinase

关联疾病

疾病名称 别名
Mycobacterium Tuberculosis 1

Tuberculosis

Tuberculoma

Tuberculosis, Susceptibility To

Mycobacterium Tuberculosis, Susceptibility To, 1

Mtbs1

TB
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00403 ADPGK Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS19980 Adpgk Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS26484 Adpgk Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ADPGK RGD RGD:1306103
Mus musculus ADPGK MGD MGI:1919391
Macaca mulatta ADPGK VGNC VGNC:69692
Bos taurus ADPGK VGNC VGNC:25689
Canis familiaris ADPGK VGNC VGNC:37669
Felis catus ADPGK VGNC VGNC:59651
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