2. Gene
  3. AIFM1 - Aifm1 apoptosis inducing factor, mitochondria associated 1 Gene

AIFM1 - Aifm1 apoptosis inducing factor, mitochondria associated 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Aif; Pdcd8

基因 ID: 83533 | 基因类型: protein coding

关于 AIFM1

功能概要

Predicted to enable DNA binding activity; FAD binding activity; and NAD(P)H oxidase H2O2-forming activity. Involved in several processes, including cellular response to lipid; cellular response to nitric oxide; and cellular response to oxygen-glucose deprivation. Located in cytosol; mitochondrion; and nucleus. Biomarker of middle cerebral artery infarction; retinal detachment; retinitis pigmentosa; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease X-linked recessive 4; X-linked deafness 5; and combined Oxidative Phosphorylation deficiency 6. Orthologous to several human genes including TXNDC12 (thioredoxin domain containing 12). [provided by Alliance of Genome Resources, Apr 2022]

AIFM1 基因产物(1)

mRNA Protein Name
NM_031356.2 NP_112646.1 apoptosis-inducing factor 1, mitochondrial precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to aldosterone IEP
IEP: 通过表达模式推断
24551180 RGD
involved in cellular response to estradiol stimulus IEP
IEP: 通过表达模式推断
16776830 RGD
involved in cellular response to hydrogen peroxide IEP
IEP: 通过表达模式推断
11781347 RGD
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
14526224 RGD
involved in cellular response to nitric oxide IEP
IEP: 通过表达模式推断
18560609 RGD
involved in positive regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
20177052 RGD
involved in response to L-glutamate IEP
IEP: 通过表达模式推断
16776830 RGD
NOT involved in response to ischemia IEP
IEP: 通过表达模式推断
23685150 RGD
involved in response to ischemia IEP
IEP: 通过表达模式推断
15181376 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
11781347 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

apoptosis-inducing factor 1, mitochondrial

apoptosis-inducing factor 1, mitochondrial-like

apoptosis-inducing factor, mitochondrion-associated 1

programmed cell death 8 (apoptosis-inducing factor)

programmed cell death protein 8

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00492 AIFM1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19406 Aifm1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25898 Aifm1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens AIFM1 NCBI NCBI:9131
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