CHST9 - carbohydrate sulfotransferase 9 Gene

中文名称：碳水化合物磺基转移酶 9

种属: Homo sapiens

同用名: GalNAc4ST2; GALNAC4ST-2

关于 CHST9

功能概要

该基因编码的蛋白质属于磺基转移酶 2 家族。它定位于高尔基体膜，催化硫酸盐转移到 N-聚糖和 O-聚糖中非还原性 N-乙酰半乳糖胺 (GalNAc) 残基的第 4 位。碳水化合物上的硫酸盐基团赋予糖蛋白、糖脂和蛋白多糖高度特异性的功能，并且对细胞间相互作用、信号转导和胚胎发育至关重要。已经描述了该基因的可变剪接转录物变体。[RefSeq 提供，2011 年 8 月]

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Sulfate groups on carbohydrates confer highly specific functions to glycoproteins, glycolipids, and proteoglycans, and are critical for cell-cell interaction, signal transduction, and embryonic development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Aug 2011]