2. Gene
  3. Thbd - thrombomodulin Gene

Thbd - thrombomodulin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 83580 | 基因类型: protein coding

关于 Thbd

功能概要

Predicted to enable calcium ion binding activity and transmembrane signaling receptor activity. Involved in response to X-ray; response to cAMP; and response to lipopolysaccharide. Located in apicolateral plasma membrane; extracellular space; and vacuolar membrane. Used to study acute kidney failure. Biomarker of adult respiratory distress syndrome; hypertension; ischemia; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including acute kidney failure; atypical hemolytic-uremic syndrome; cerebrovascular disease (multiple); rheumatoid arthritis; and thrombophilia (multiple). Orthologous to human THBD (thrombomodulin). [provided by Alliance of Genome Resources, Apr 2022]

Thbd 基因产物(1)

mRNA Protein Name
NM_031771.2 NP_113959.1 thrombomodulin precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to X-ray IEP
IEP: 通过表达模式推断
12057911 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
17090405 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
12611420 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apicolateral plasma membrane IDA
IDA: 通过直接分析推断
9272431 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
12611420 RGD
located in vacuolar membrane IDA
IDA: 通过直接分析推断
9272431 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

thrombomodulin

thrombomdulin

重组 Thbd 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74519 Thrombomodulin Protein, Rat (HEK293, His) O35370 (I17-S517) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14478 THBD Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18261 Thbd Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24740 Thbd Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Thbd NCBI NCBI:7056
Mus musculus Thbd NCBI NCBI:21824
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