1. Gene
  2. Ugcg - UDP-glucose ceramide glucosyltransferase Gene

Ugcg - UDP-glucose ceramide glucosyltransferase Gene

中文名称:UDP-葡萄糖神经酰胺葡糖基转移酶

种属: Rattus norvegicus

基因 ID: 83626 | 基因类型: protein coding

关于 Ugcg

Primary_assembly 5: 74,032,978-74,065,393 forward strand.mRatBN7.2:CM026978.1

This gene has 1 transcript (splice variant), 212 orthologues and is associated with 4 phenotypes. Biased expression in Adrenal (RPKM 17.6), Spleen (RPKM 95.4) and 9 other tissues.

功能概要

该基因编码的蛋白可启动神经酰胺葡糖基转移酶活性。预计将涉及多个过程,包括角化信封组装;葡萄糖神经酰胺生物合成过程;和皮肤发育。位于高尔基体膜。是膜的组成部分。与人 UGCG(UDP-葡萄糖神经酰胺葡糖基转移酶)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables ceramide glucosyltransferase activity. Predicted to be involved in several processes, including cornified envelope assembly; glucosylceramide biosynthetic process; and skin development. Located in Golgi membrane. Is integral component of membrane. Orthologous to human UGCG (UDP-glucose ceramide glucosyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Ugcg 基因产物(1)

mRNA Protein Name
NM_031795.2 NP_113983.1 ceramide glucosyltransferase
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ceramide glucosyltransferase activity IDA
IDA: 通过直接分析推断
10393098 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi membrane IDA
IDA: 通过直接分析推断
9867864 RGD
located in membrane IDA
IDA: 通过直接分析推断
9867864 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Ugcg 蛋白结构

Glucosylceramide_synthase

Glucosylceramide_synthase: cd02520 (50 - 279)

  • 0
  • 100
  • 200
  • 300
  • 394 a.a.
蛋白主名 其他名称

ceramide glucosyltransferase

GCS

GLCT-1

UDP-glucose:N-acylsphingosine D-glucosyltransferase

UDP-glucose:ceramide glycosyltransferase

glucosylceramide synthase

glycosylceramide synthase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ugcg NCBI NCBI:7357